Feasibility study on appication of synthetic biology approaches to high yield production of Mycosporine-like Amino Acids for use as UV-protectants.

应用合成生物学方法高产生产用作紫外线防护剂的类菌孢素氨基酸的可行性研究。

• 批准号: 131177
• 金额: $ 9.55万
• 依托单位: CRODA EUROPE LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=131177
• 关键词: Feasibility; study; appication; synthetic; biology

The project is a collaboration between Newcastle University and Croda Europe to develop tools to produce natural UV-absorbing substances for use in sunscreens. These materials are produced by microorganisms which survive in ecosystems which are exposed to high light intensity and are an important mechanism for protecting cells against the harmful effects of UV-light. The project uses the genes from a natural organism (algae) in a bacterium with a long history of safe use in the manufacture of amino acids and vitamins. The manufacturing process is renewable and uses sustainable raw materials which do not compete with the food chain. The products developed in the project will be shown to be safe to humans and the environment and will reduce the overall dependence on petrochemical resources.

该项目是纽卡斯尔大学和 Croda Europe 之间的合作，旨在开发生产用于防晒霜的天然紫外线吸收物质的工具。这些材料是由生存在暴露于高光强度的生态系统中的微生物产生的，是保护细胞免受紫外线有害影响的重要机制。该项目使用了细菌中天然生物体（藻类）的基因，该细菌在氨基酸和维生素的生产中具有悠久的安全使用历史。制造过程是可再生的，并使用不与食物链竞争的可持续原材料。该项目开发的产品将被证明对人类和环境是安全的，并将减少对石化资源的整体依赖。