Optimising progress towards elimination of malaria

优化消除疟疾的进展

• 批准号: DP200100747
• 负责人: Prof Jennifer Flegg
• 金额: $ 36.9万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-04-28 至 2024-04-27
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200100747
• 关键词: Optimising; progress; towards; elimination; malaria

The project aims to advance mathematical knowledge by developing novel tools appropriate for modelling disease elimination. We will apply these new mathematical tools to the significant problem of malaria elimination in Vietnam. The expected outcomes are new tools for modelling disease elimination on a fine spatial resolution with heterogeneities in individual patient characteristics, calibrating models to household level data on disease transmission and designing intervention strategies for maximum effect on disease transmission. The innovative combination of modelling, inference and optimisation ensures that the mathematical methods developed will be broadly applicable to modelling elimination strategies for other infectious diseases.

该项目旨在通过开发适用于模拟疾病消除的新工具来推进数学知识。我们将把这些新的数学工具应用于越南消灭疟疾的重大问题。预期的成果是新的工具，用于在精细的空间分辨率上建立消除疾病的模型，并考虑到个别患者特征的不均匀性，根据家庭一级的疾病传播数据校准模型，并设计干预战略，以最大限度地减少疾病传播。建模、推理和优化的创新组合确保了所开发的数学方法将广泛适用于其他传染病的消除策略建模。