CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
批准号:
2160621
负责人:
DANIEL J UHLRICH
金额:
$12.64万
依托单位国家:
美国
项目类别:
财政年份:
1990
资助国家:
美国
项目状态:
已结题
起止时间:
1990-07-01 至 1996-03-31
中文摘要
丘脑外侧膝状体核(LGN)位于丘脑的主要核团中。
眼睛和视觉皮层之间的神经通路,它控制着
在很大程度上是通过影响
脑干中特定的核团。 脑干的通路可以
强烈影响LGN,并被认为反映了行为状态,
例如唤醒或注意以及眼球运动的发生。 然而,
这些脑干回路的解剖学和生理学并不是很好
明白 这项研究将提供一个全面的,多学科的
描述脑干的结构和功能影响,
的LGN。 在这样做时,这些研究将更普遍地阐明
丘脑在将感觉信息传递到e皮质中的作用,以及
他们将有助于理解一个关键的神经元素的作用,
视野
目的1和3是证明电和化学的影响,
单个脑干核团在细胞外和细胞内
LGN细胞对视觉刺激的反应。 目的2和4是描述,在
在光镜和电镜水平上,
顺行示踪剂、脑干神经元的形态和超微结构
投射到外侧膝状体和其他丘脑核团。 目标5是确认和
描述了关键的丘脑通路,脑干通过这些通路间接地
控制LGN。
英文摘要
The thalamic lateral geniculate nucleus (LGN) is found in the primary
neural pathway between the eye and visual cortex, and it controls the flow
of visual information to the brain in large measure through the influence
of specific nuclei in the brainstem. Pathways from the brainstem can
powerfully effect the LGN and are believed to reflect behavioral states,
such as arousal or attention and the occurrence of eye movements. HOwever,
the anatomy and physiology of these brainstem circuits are not well
understood. This research will provide a comprehensive, multi-disciplinary
description of the structural and functional influences of the brainstem on
the LGN. In doing so, these studies will elucidate, more generally, the
role of the thalamus in relaying sensory information to the e cortex, and
they will aid in understanding the role of a key neural element underlying
vision.
Aims 1 and 3 are to demonstrate the effects of electrical and chemical
activation of individual brainstem nuclei on the extra- and intracellular
responses of LGN cells to visual stimuli. Aims 2 and 4 are to describe, at
the light and electron microscopic level by means of retrograde and
anterograde tracers, the morphology and ultrastructure of brainstem neurons
that project to the LGN and other thalamic nuclei. Aim 5 is to confirm and
describe key thalamic pathways through which the brainstem indirectly
controls the LGN.
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会议论文
MODULATION OF SENSORY TRANSMISSION IN THE THALAMUS
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批准号:2165558
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项目类别:
-
资助金额:$17.11万
-
财政年份:1995
-
负责人:DANIEL J UHLRICH
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依托单位:
MODULATION OF SENSORY TRANSMISSION IN THE THALAMUS
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批准号:2391753
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项目类别:
-
资助金额:$17.71万
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财政年份:1995
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负责人:DANIEL J UHLRICH
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依托单位:
MODULATION OF SENSORY TRANSMISSION IN THE THALAMUS
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批准号:2165557
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项目类别:
-
资助金额:$16.95万
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财政年份:1995
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负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEMS
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批准号:3263033
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项目类别:
-
资助金额:$9.52万
-
财政年份:1990
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:3263032
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项目类别:
-
资助金额:$12.22万
-
财政年份:1990
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
-
批准号:2391687
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项目类别:
-
资助金额:$11.39万
-
财政年份:1990
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:2160623
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项目类别:
-
资助金额:$11.26万
-
财政年份:1990
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
-
批准号:3263031
-
项目类别:
-
资助金额:$11.75万
-
财政年份:1990
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:3263030
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项目类别:
-
资助金额:$10.81万
-
财政年份:1990
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:2684511
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项目类别:
-
资助金额:$11.84万
-
财政年份:1990
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:3263028
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项目类别:
-
资助金额:$8.23万
-
财政年份:1986
-
负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:3263025
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项目类别:
-
资助金额:$6.6万
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财政年份:1986
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负责人:DANIEL J UHLRICH
-
依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:3263027
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项目类别:
-
资助金额:$3.67万
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财政年份:1986
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负责人:DANIEL J UHLRICH
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依托单位:
CONTROL OF CENTRAL VISUAL PATHWAYS BY THE BRAINSTEM
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批准号:3263029
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项目类别:
-
资助金额:$8.55万
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财政年份:1986
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负责人:DANIEL J UHLRICH
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依托单位:
RETINOGENICULATE PATHWAY DEVELOPMENT IN THE CAT
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批准号:3038440
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项目类别:
-
资助金额:$2.5万
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财政年份:1985
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负责人:DANIEL J UHLRICH
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依托单位:
STRUCTURE & FUNCTION RELATIONSHIPS IN MACAQUE VISUAL CORTEX, INVITRO
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批准号:5219937
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:DANIEL J UHLRICH
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依托单位:--
HISTAMINE MODULATION OF CENTRAL VISUAL PATHWAYS
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批准号:3718883
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:DANIEL J UHLRICH
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依托单位:
海外基金