Molecular networks underlying mitochondrial biogenesis in humans

人类线粒体生物发生的分子网络

• 批准号: DP200103542
• 负责人: Prof David Bishop
• 金额: $ 34.88万
• 依托单位: Victoria University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200103542
• 关键词: Molecular; networks; underlying; mitochondrial; biogenesis

Mitochondria are essential for life, and we propose a highly-innovative approach (employing multiple, cutting-edge ‘omic’ technologies and bioinformatics) to advance the fundamental understanding of how mitochondria respond and adapt to exercise in humans. The project outcomes should include significant new knowledge and advanced expertise that can be used by others to facilitate additional research outcomes. The project anticipates the contribution of innovative tools for molecular biology research, benefiting therapeutic and biotechnology applications. This project will support advanced training of young researchers in frontier technologies, which will expand Australian research capabilities and help produce a higher quality workforce.

线粒体对于生命至关重要，我们提出了一种高度创新的方法（采用多种尖端的“组学”技术和生物信息学）来促进对线粒体如何响应和适应人类运动的基本理解。 项目成果应包括重要的新知识和先进的专业知识，可供其他人使用，以促进额外的研究成果。该项目预计创新工具将为分子生物学研究做出贡献，有益于治疗和生物技术应用。该项目将支持年轻研究人员在前沿技术方面的高级培训，这将扩大澳大利亚的研究能力并帮助培养更高素质的劳动力。