PHYSIOLOGICAL AND BEHAVIORAL CORRELATES OF INFANT COLIC

婴儿绞痛或长时间哭泣，在其他方面健康的情况下 婴儿一直是父母和儿科医生困惑的来源。 这在很大程度上是由于缺乏关于其起源的具体证据。 更令人困惑的是，绞痛可能会对 后来的婴儿行为或父母对该行为的看法。目的 拟议的研究的目的是通过调查 婴幼儿绞痛和腹痛的生理和行为影响因素及相关因素 研究其对婴儿后期发育的影响。向着这些目标， 提出了两项研究。一项是一项纵向研究，旨在 前瞻性地识别和跟踪一组绞痛和非绞痛婴儿 从出生到十个月大。另外两组，一组是易怒的组 经常哭泣但不符合绞痛标准的人，以及 表现出过度的胃肠道症状，但不会过度哭泣 也会被追随。绞痛的出现将在其发病时确定。 以及通过使用日记获得与绞痛相关的行为。 轶事报道和我们对在 绞痛表明，婴儿表现出胃肠道疼痛。 对成年人使用非侵入性胃电(胃电)的研究表明 有报告称胃肠道不适与心律失常有关。我们 建议记录绞痛婴儿在基线和绞痛期间的卵子 确定正常节律的变化是否与 有绞痛的哭闹行为。确定婴儿的贡献 气质与绞痛的发生及绞痛对婴儿的影响 行为一旦消散，我们建议测量婴儿的反应性 以及在出生时、5个月和10个月出生时的监管 实验室程序和父母评级。第二项横断面研究 被建议用来检测胃肌电活动的发展 在生命的第一年内使用卵子。到目前为止，还没有 使用这一测量方法的研究已经存在。这项研究将先于纵向 研究的结果对于我们理解 与绞痛相关的生理变化。这两项研究都将有助于 对婴儿健康和发育的几个领域具有重要意义的信息。

Infant colic or prolonged, inconsolable crying in an otherwise healthy infant has been a source of confusion for parents and pediatricians alike. Much of this is due to the lack of concrete evidence as to its origins. Adding to the confusion is the finding that colic may have an impact on later infant behavior or parent perceptions of that behavior. The purpose of the proposed research is to address these issues by investigating the physiological and behavioral antecedents and correlates of infant colic and to examine its influences on later infant development. Toward these ends, two studies are proposed. One is a longitudinal study designed to prospectively identify and follow a group of colic and non-colic infants from birth to ten months of age. Two other groups, one an irritable group that cries frequently but does not meet colic criteria, and one that exhibits excessive gastrointestinal symptoms but not excessive crying will also be followed. The emergence of colic will be identified at its onset and behaviors associated with colic obtained through the use of diaries. Anecdotal reports and our preliminary study of behaviors exhibited during a colic bout suggest that infants are expressing gastrointestinal pain. Work with adults using the non-invasive electrogastrogram (EGG) has shown reports of gastrointestinal upset to be associated with dysrhythmia. We propose to record the EGGs of colic infants during a baseline and colic condition to determine whether changes in normal rhythms are associated with colic cry behavior. To determine the contribution of infant temperament to the emergence of colic and whether colic influences infant behavior once it has dissipated, we propose to measure infant reactivity and regulation at birth, five months, and 10 months of age through laboratory procedures and parental ratings. A second cross-sectional study is proposed to examine the development of gastric myoelectric activity within the first year of life using the EGG. To date, no developmental studies using this measure exist. This study will precede the longitudinal study as the results are essential to our understanding of the physiological changes associated with colic. Both studies will contribute important information to several areas of infant health and development.