REGULATION OF COLLAGENASE GENE EXPRESSION BY IL-1 & TNF

IL-1对胶原酶基因表达的调控

• 批准号: 2078013
• 负责人: MATTHEW P VINCENTI
• 金额: $ 2.86万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2078013
• 关键词: collagenase; gene expression; genetic transcription; interleukin 1; messenger RNA; molecular pathology; posttranscriptional RNA processing; rheumatoid arthritis; tumor necrosis factor alpha

项目成果

Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.

与正常结肠上皮相比，结直肠肿瘤中基质金属蛋白酶 2 (MMP-2) 的激活和抑制之间的平衡发生了改变。

• DOI: 10.1023/a:1016456914723
• 发表时间: 2002
• 期刊: Digestive diseases and sciences
• 影响因子: 3.1
• 作者: Ornstein,DeborahL;Cohn,KennethH
• 通讯作者: Cohn,KennethH

Using inhibitors of metalloproteinases to treat arthritis. Easier said than done?

使用金属蛋白酶抑制剂治疗关节炎。

• DOI: 10.1002/art.1780370802
• 发表时间: 1994
• 期刊: Arthritis and rheumatism
• 作者: Vincenti,MP;Clark,IM;Brinckerhoff,CE
• 通讯作者: Brinckerhoff,CE