Can exercise slow down the epigenetic ageing clock?

运动可以减缓表观遗传衰老时钟吗？

• 批准号: DP200101830
• 负责人: Prof Nir Eynon
• 金额: $ 31.25万
• 依托单位: Victoria University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200101830
• 关键词: exercise; slow; down; epigenetic; ageing

The aged population accounts for a significant amount of Australia’s health budget. This project aims to uncover novel molecular biomarkers that slow the ageing process and maintain good health for longer. This project aims to use innovative epigenetic analysis to study the molecular ‘clocks’ of young and old populations and to test whether exercise can slow the ageing process. This is expected to lead to a better understanding of how humans respond to changing environments during their lifetime, and will underpin the development of evidence-based personalised health interventions to keep Australians healthier for longer.

老年人口占澳大利亚卫生预算的很大一部分。该项目旨在发现新的分子生物标志物，以减缓衰老过程并保持健康更长时间。该项目旨在利用创新的表观遗传学分析来研究年轻人和老年人的分子“时钟”，并测试运动是否能减缓衰老过程。预计这将使人们更好地了解人类在其一生中如何应对不断变化的环境，并将巩固以证据为基础的个性化健康干预措施的发展，使澳大利亚人更健康。