The "Personal REspiratory Disease Index Calculation Technique" Project (PREDICT)

「个人呼吸系统疾病指数计算技术」项目（PREDICT）

• 批准号: 133095
• 金额: $ 8.92万
• 依托单位: CAMBRIDGE RESPIRATORY INNOVATIONS LIMITED
• 依托单位国家: 英国
• 项目类别: Feasibility Studies
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=133095
• 关键词: Personal; REspiratory; Disease; Index; Calculation

Cambridge Respiratory Innovations Limited (CRiL) has been awarded an Innovate UK grant to complete the development of a respiratory performance index based on analysis of CO2 in normal tidal breathing. The CRiL team have developed a low-cost personal respiratory monitor which measures the CO2 in normal tidal breathing. Their goal is to develop personal respiratory monitors to help people who suffer from a range of respiratory diseases to better manage their condition. CRiL's N-Tidal C is powered by a unique advanced expitaxially-grown LED CO2 sensor. Although it uses advanced technology, the medical device is very easy to use, since it requires no forced expiration. CRiL's low-cost medical device accurately measures CO2 concentrations more than 50 times per second in normal tidal breathing. CRiL's N-Tidal C has recently been used in a pivotal exploratory clinical study with patients with Chronic Obstuctive Pulmonary Disease (COPD). The breathing records demonstrate that clear changes in the breath record start to occur in COPD about 48 hours before an exacerbation. Through this research project the CRiL team will develop an automated alert for the next-generation personal monitor, the N-Tidal B, which will indicate to the patient that their respiratory condition is starting to deteriorate. The development of CRiL's innovative technology has been supported previously by Innovate UK, SBRI Healthcare and some healthcare charities.

剑桥呼吸创新有限公司(CRIL)获得了英国创新基金，以完成一项基于正常潮气呼吸中二氧化碳分析的呼吸性能指数的开发。CRIL团队开发了一种低成本的个人呼吸监测仪，可以测量正常潮气呼吸中的二氧化碳。他们的目标是开发个人呼吸监测仪，帮助患有一系列呼吸道疾病的人更好地管理自己的病情。CRIL的N型潮汐C由独特的先进外延生长的LED二氧化碳传感器提供动力。虽然它使用了先进的技术，但医疗设备非常容易使用，因为它不需要强制过期。CRIL的低成本医疗设备在正常潮气呼吸时每秒准确测量二氧化碳浓度超过50次。CRIL的N-TdaC最近被用于慢性阻塞性肺疾病(COPD)患者的关键探索性临床研究。呼吸记录表明，COPD患者在病情加重前48小时左右，呼吸记录就开始发生明显的变化。通过这一研究项目，CRIL团队将为下一代个人监测器N-TideB开发自动警报，该警报将向患者指示他们的呼吸状况开始恶化。CRIL创新技术的开发此前曾得到Innovate UK、SBRI Healthcare和一些医疗慈善机构的支持。