Rapid detection and categorisation of organisms from whole blood in cases of sepsis

Momentum Bioscience的成立旨在开发医院微生物学实验室内临床样本的快速检测，支持全球对抗抗生素耐药性的斗争以及改善抗菌药物管理的需求。败血症（血液中毒）比肠癌、乳腺癌和前列腺癌的死亡人数总和还要多，但败血症的症状往往是非特异性的，导致诊断延误。败血症的标准实验室测试是血液培养，它检测可以在患者血液中发现的大范围细菌，但有时需要几天才能给出结果。我们的研究将着眼于在短短3小时内检测和分类这些细菌的可行性，帮助医生更快地为患者选择正确的抗生素。该项目将探索从血液中捕获和浓缩细菌的新方法，以便使用Momentum已经开发的分子技术进行检测。

Momentum Bioscience was founded to develop rapid tests for clinical specimens within the hospital microbiology laboratory, supporting the global fight against antibiotic resistance and the need for improved antimicrobial stewardship. Sepsis (blood poisoning) kills more people than bowel, breast and prostate cancer combined but symptoms of sepsis are frequently non-specific, leading to a delay in diagnosis. The standard laboratory test for sepsis is blood culture, which detects a large range of germs that can be found in the patient’s blood but can sometimes take several days to give a result. Our study will look at the feasibility of detecting and categorising these germs in just 3 hours, helping doctors choose the right antibiotic for the patient more quickly. This project will explore new approaches to capturing and concentrating germs from blood so they can be detected using molecular technology already developed by Momentum.