How ecology shapes the viromes of wild birds

生态学如何塑造野生鸟类的病毒体

• 批准号: DE200100977
• 负责人: Dr Michelle Wille
• 金额: $ 23.88万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-06-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE200100977
• 关键词: How; ecology; shapes; viromes; wild

This project will reveal the host factors associated with the diversity, evolution and dynamics of viruses using state-of-the-art metatranscriptomics in Australian wild birds. The structure of virus communities and their associated ecological drivers in wild animal hosts remain a black-box, even though they are the largest source of viral diversity in nature. This project expects to generate key insights into host-associated drivers of viral community dynamics and the subsequent effect of anthropogenic factors such as urbanisation and poultry production. Identifying host factors that affect viral ecology in wild birds will constitute a cornerstone in understanding the emergence of virulent viruses and/or their spread to poultry or humans

该项目将利用澳大利亚野生鸟类最先进的宏转录组学揭示与病毒多样性、进化和动态相关的宿主因素。野生动物宿主中病毒群落的结构及其相关的生态驱动因素仍然是一个黑匣子，尽管它们是自然界病毒多样性的最大来源。该项目期望对病毒群落动态的宿主相关驱动因素以及城市化和家禽生产等人为因素的后续影响产生重要见解。确定影响野生鸟类病毒生态的宿主因素将成为了解强毒病毒的出现和/或它们向家禽或人类传播的基石