Characterisation of the beneficial vs toxic forms of selenium in the diet

饮食中硒的有益与有毒形式的表征

• 批准号: DP200102670
• 负责人: Prof Hugh Harris
• 金额: $ 32.31万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200102670
• 关键词: Characterisation; beneficial; vs; toxic; forms

This project aims to examine how dietary selenium is converted into essential proteins and beneficial compounds that mitigate against a broad range of human diseases; or alternatively, into toxic molecules. Cutting-edge methodologies should resolve significant unknowns in selenium metabolism, to provide definitive dietary guidelines and to explore how selenium can treat and protect against disease. Expected outcomes from this national and international collaboration include expert training for young biochemical researchers and refinements to novel analytical techniques. Results should benefit the food and agricultural sectors to provide tailored products locally and for export, as well as enhanced health opportunities for all Australians.

该项目旨在研究膳食硒如何转化为必需蛋白质和有益化合物，以减轻各种人类疾病;或者，转化为有毒分子。尖端的方法应该解决硒代谢中的重大未知因素，提供明确的饮食指南，并探索硒如何治疗和预防疾病。这项国家和国际合作的预期成果包括为年轻的生物化学研究人员提供专家培训，并改进新的分析技术。研究结果应有利于食品和农业部门在当地提供量身定制的产品和出口产品，并为所有澳大利亚人提供更多的健康机会。