Linking arterial, brain and cognitive integrity in healthy older adults.

将健康老年人的动脉、大脑和认知完整性联系起来。

• 批准号: DP200101471
• 负责人: Prof Frini Karayanidis
• 金额: $ 37.85万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200101471
• 关键词: Linking; arterial; brain; cognitive; integrity

This project aims to demonstrate that engaging the brain’s prefrontal cortex, an area that is highly sensitive to ageing, can improve the function of arteries that supply blood to this brain region. Using an innovative optical imaging methodology that maps the brain’s regional arterial health, it aims to generate new knowledge about the link between this arterial system and the progressive decline in cognitive control ability and in prefrontal cortex structure and function in healthy older adults. This interdisciplinary, international collaboration aims to put Australia at the forefront of brain optical imaging methods that may have significant benefits by informing approaches to promote and maintain healthy brain and cognition in old age.

该项目旨在证明，参与对衰老高度敏感的大脑前额叶皮层可以改善向该大脑区域供血的动脉功能。它使用一种创新的光学成像方法来绘制大脑区域动脉的健康状况，旨在产生关于该动脉系统与健康老年人认知控制能力以及前额皮质结构和功能逐渐下降之间联系的新知识。这项跨学科的国际合作旨在使澳大利亚处于脑光学成像方法的前沿，这些方法可能通过提供促进和维持老年大脑健康和认知的方法而带来重大益处。