Reconnecting the ageing brain to enhance plasticity and motor learning

重新连接衰老的大脑以增强可塑性和运动学习

• 批准号: DP200101009
• 负责人: A/Prof John Semmler
• 金额: $ 20.89万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-06-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200101009
• 关键词: Reconnecting; ageing; brain; enhance; plasticity

The ability to execute and learn skillful actions deteriorates with advancing age, but the cause remains elusive. The main aim of this project is to use new neurophysiological techniques to examine the age-related changes in brain function that contribute to reduced movement control in healthy older adults. The research will use multimodal approaches to reveal the causal role of age-related changes in specific brain networks to motor behaviour and learning. The outcomes will provide significant new knowledge that may help to optimise the design of targeted interventions aimed at rejuvenating brain function and movement quality in the elderly.

随着年龄的增长，执行和学习熟练动作的能力会下降，但原因仍然难以捉摸。该项目的主要目的是使用新的神经生理学技术来检查与年龄相关的大脑功能变化，这些变化有助于健康老年人的运动控制能力下降。该研究将使用多模式方法来揭示特定大脑网络中与年龄相关的变化对运动行为和学习的因果作用。这些结果将提供重要的新知识，可能有助于优化旨在恢复老年人大脑功能和运动质量的有针对性的干预措施的设计。