AEROSOL SAMPLER PERFORMANCE CHARACTERISTICS

该项目的目的是提供一个更好的科学 开发适用于健康领域的新采样器的框架- 工作场所气溶胶的相关测量。新的粒度选择 标准，预计将成为新的工业卫生的基础 标准，正在刺激对采样器的严格检查，目前 （根据这些标准）和开发新的 装置. 目前发展的一个主要限制因素， 这种工具的设计在于缺乏足够的理解， 实际抽样过程本身，特别是决定 空气中的颗粒被吸入采样的效率 设备与外部环境空气隔离。因此， 与所需性能特征匹配的实用仪器 基本上是经验主义的。因此，拟议工程计划包括 对一些杰出的相关科学问题进行科学调查， 问题.目标将是产生定量工作 未来设计实用粒径选择性 取样装置 工作本身的进行将涉及以实验室为基础的实验性 研究，使用已经建立在广泛的技术， 主要研究者之前参与的研究 在过去的15年里。这将得到物理和 统计建模，旨在使一般化的 获得科学知识以取得实际成果。 鉴于目前正朝着 工人评估方法的国际协调 暴露于气溶胶。

The aim of the proposed project is to provide an improved scientific framework for developing new samplers suitable for use in the health- related measurement of workplace aerosols. New particle size-selective criteria, which are expected to form the basis of new industrial hygiene standards, are stimulating a critical examination of samplers, currently in use (in the light of those criteria) and the development of new devices. A major limiting factor in the current apprnach to the development and design of such instruments lies in the lack of sufficient understanding of the actual sampling process itself, in particular of the factors governing the efficiency with which airborne particles are drawn into the sampling device from the ambient air outside. As a result, the development of practical instruments matching desired performance characteristics has so far been largely empirical. The proposed project therefore comprises a scientific enquiry into some of the outstanding relevant scientific questions. The objective will be to generate quantitative working guidelines for the future design of practical particle size-selective sampling devices. The conduct of the work itself will involve laboratory-based experimental research, using techniques which have been established in extensive previous research with which the principal investigator has been associated for the past 15 years. This will be backed up by physical and statistical modeling aimed at enabling the generalization of the scientific knowledge gained towards practical outcomes. The project is particularly timely in view of the current move towards international harmonization on methodology for the assessment of worker exposures to aerosols.