The processing of fear in the medial temporal lobe

内侧颞叶的恐惧处理

• 批准号: FT190100697
• 负责人: Dr Nathan Holmes
• 金额: $ 56.19万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT190100697
• 关键词: processing; fear; medial; temporal; lobe

The aim of this project is to identify how fear affects information processing in the medial temporal lobe (MTL). It is significant in providing the first systematic assessment of how fear alters processing of different types of information in the MTL, including the innocuous; and how fear affects processing of memories in MTL networks, including their integration. The expected outcomes are basic knowledge regarding these effects of fear, and a theory of MTL function in which they are explained. The benefit of this knowledge is a better understanding of how information is processed in a normal brain, and therefore, disturbances to information processing in fear-related disorders (e.g., over-generalization of fear in post-traumatic stress).

该项目的目的是确定恐惧如何影响内侧颞叶（MTL）的信息处理。它对于首次系统评估恐惧如何改变 MTL 中不同类型信息（包括无害信息）的处理具有重要意义。以及恐惧如何影响 MTL 网络中的记忆处理，包括它们的整合。预期的结果是关于恐惧的这些影响的基本知识，以及解释它们的 MTL 功能理论。这些知识的好处是更好地理解信息在正常大脑中是如何处理的，从而更好地理解与恐惧相关的疾病中信息处理的干扰（例如，创伤后应激中恐惧的过度概括）。