GORDON CONFERENCE--PROTONS AND MEMBRANE REACTIONS

戈登会议——质子和膜反应

• 批准号: 2187805
• 负责人: STEVE SCHEINER
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-01-01 至 1994-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2187805
• 关键词: bacteriorhodopsins; hydrogen transport; meeting /conference /symposium; membrane activity; oxidative phosphorylation; photosynthetic reaction centers; travel

The coupling of a proton gradient across a membrane to energy consumption such as phosphate bond formation is widespread, occurring also in cell development and differentiation, regulation, and motility, photosynthesis, and acidification of the stomach. But the mechanism by which the protons are conducted is only partially understood. Each research group tends to focus on one particular system. As insights are gained in each of these systems, it is important that this information be shared with all those working on the general problem as these insights will undoubtedly prove useful in more than one system. It is for just this purpose of bringing together researchers working on disparate facets of proton transport that the first Gordon Conference on Protons and Membrane Reactions was established in 1985. This meeting traditionally brings together researchers treating a variety of proton-conducting systems using a host of different approaches. One of the strengths of this meeting is the broad range of backgrounds of the scientists which encourages cross-pollination as the sessions address a diverse range of questions. The triannual occurrence of the meeting allows sufficient intervals that the work presented is fresh and interesting. The 1994 Conference will focus on a number of issues beginning with a careful documentation of what is understood about proton transfer in small, well-defined systems. The potential of information from synthetic proton conductors will be discussed, as will recent data dealing with structures of biologically active conductors. Sessions on bacteriorhodopsin and photosynthetic reaction centers will center about recent knowledge about the paths of the protons through the proteins. Another session will be devoted to the various ways in which water molecules can be directly involved in the conduction process and another on proton motion along boundary regions. Protons will be contrasted with other cations in Session 8, followed by recent developments in oxidative phosphorylation.

跨膜的质子梯度与能量消耗的耦合 例如磷酸键的形成广泛存在，也存在于细胞中 发育和分化，调节和动力，光合作用， 以及胃部酸化。但是质子通过的机制 人们对此只有部分了解。每个研究小组都倾向于 专注于一个特定的系统。随着对其中每一项的深入了解 系统，重要的是要将这些信息与所有 致力于解决一般问题，这些见解无疑将证明 在多个系统中有用。它就是为了把这个目的 研究人员共同致力于质子运输的不同方面 关于质子和膜反应的第一次戈登会议 成立于1985年。这一会议传统上是将 研究人员使用宿主处理各种质子传导系统 不同的方法。这次会议的优势之一是广泛的 鼓励异花授粉的科学家的背景范围 因为会议讨论了一系列不同的问题。三年一度的 会议的召开有足够的时间间隔，使工作 呈现的是新鲜和有趣的。1994年的会议将侧重于 从仔细记录问题开始的许多问题 了解质子在小型、定义明确的系统中的转移。这个 来自合成质子导体的信息的潜力将是 讨论，以及处理生物学结构的最新数据 有源导体。细菌视紫红质与光合作用会议 反应中心将集中于关于生物多样性路径的最新知识 通过蛋白质的质子。另一场会议将专门讨论 水分子可以通过多种方式直接参与 传导过程和另一个关于质子沿边界区域运动的过程。 在第八节课中，质子将与其他阳离子进行对比，接下来是 氧化磷酸化的最新进展。