REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
批准号:
2111482
负责人:
KHEW-VOON CHIN
金额:
$7.24万
依托单位国家:
美国
项目类别:
财政年份:
1995
资助国家:
美国
项目状态:
已结题
起止时间:
1995-05-01 至 2000-04-30
关键词:
P glycoprotein cell type chloramphenicol acetyltransferase drug interactions flow cytometry gene deletion mutation gene expression genetic promoter element genetic regulation molecular cloning multidrug resistance neoplasm /cancer genetics neoplastic process nucleic acid sequence oncogenes regulatory gene tissue /cell culture transcription factor transfection tumor suppressor genes
中文摘要
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英文摘要
The role of p53 in the regulation of MDR1 expression is crucial to the
understanding of the mechanisms of development of the multidrug resistance
phenotype in cancers. Results from these studies could have significant
implications for the activation of the MDR1 gene during tumor progression
associated with genetic alterations in p53, and could potentially provide
novel alternatives to the development and design of specific treatment
strategies for human malignancies.
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资助金额:$21.16万
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财政年份:1999
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财政年份:1997
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REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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批准号:2700609
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资助金额:$7.24万
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财政年份:1995
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负责人:KHEW-VOON CHIN
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依托单位:
REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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批准号:2414392
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项目类别:
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资助金额:$7.24万
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财政年份:1995
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负责人:KHEW-VOON CHIN
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依托单位:
REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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批准号:2895292
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项目类别:
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资助金额:$7.24万
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财政年份:1995
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负责人:KHEW-VOON CHIN
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依托单位:
REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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批准号:2111483
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项目类别:
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资助金额:$7.24万
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财政年份:1995
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负责人:KHEW-VOON CHIN
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REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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批准号:2008150
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资助金额:$12.01万
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财政年份:1993
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负责人:KHEW-VOON CHIN
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依托单位:
REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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批准号:3460631
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项目类别:
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财政年份:1993
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依托单位:
REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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资助金额:$9.63万
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财政年份:1993
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依托单位:
REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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批准号:2099141
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财政年份:1993
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REGULATION OF MULTIDRUG RESISTANCE GENE EXPRESSION
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依托单位:
海外基金