课题基金 / 基金详情

DICHLOROETHYLENE AND TETRACHLOROETHANE STUDIES

DICHLOROETHYLENE AND TETRACHLOROETHANE STUDIES
二氯乙烯和四氯乙烷研究
批准号:
2308466
负责人:
ANDREW BRAUN
金额:
$176.1万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1991
资助国家:
美国
项目状态:
已结题
起止时间:
1991-09-30 至 1993-09-28

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中文摘要
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英文摘要
The objective of this project is to characterize the toxicity of the isomers of 1,2-dichloroethylene and 1,1,2,2-tetrachloroethane in Fischer 344 rats and B6C3F1 mice and to identify target organ lesions. 14-day and 13-week studies are to be conducted by dosed feed (using microencapsulated material) for cis, trans and cis/trans-dichloroethylene and 1,1,2,2-tetrachloroethane and by gavage for trans-dichloroethylene and 1,1,2,2-tetrachloroethane. In addition to characterizing the toxicity of these compounds, studies are included to confirm the bioavailability of these microencapsulated compounds after administration in feed and when administered by gavage, to establish dose proportionality.
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DICHLOROETHYLENE AND TETRACHLOROETHANE STUDIES
  • 批准号:
    2652382
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    1991
  • 负责人:
    ANDREW BRAUN
  • 依托单位:
DICHLOROETHYLENE & TETRACHLOROETHANE STUDIES
  • 批准号:
    2657114
  • 项目类别:
  • 资助金额:
    $3.36万
  • 财政年份:
    1991
  • 负责人:
    ANDREW BRAUN
  • 依托单位:
DICHLOROETHYLENE AND TETRACHLOROETHANE STUDIES
  • 批准号:
    2308469
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    1991
  • 负责人:
    ANDREW BRAUN
  • 依托单位:
CHRONIC DOSED FEED STUDY OF PHENOLPHTHALEIN
  • 批准号:
    2308013
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    1990
  • 负责人:
    ANDREW BRAUN
  • 依托单位:
海外基金