AGE-RELATED EYE DISEASE STUDY

年龄相关眼病研究

• 批准号: 2312102
• 负责人: THOMAS R FRIBERG
• 金额: $ 28.08万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-03-01 至 2000-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2312102
• 关键词: AGE; RELATED; EYE; DISEASE; STUDY

The purpose of this study, the Aged RElated Eye Disease Study (AREDS), is to enroll patients with minor to severe drusen pathology and a) follow the natural progression of macular degeneration; and b) determine if dietary supplements of multivitamins, mineral(s) or multivitamins and minerals delay the progression of the disease. Because patients enrolled will not have optically significant lens opacities, this study will also provide information on development of cataracts in individuals with macular disease. The study will provide new information regarding the progression of macular degeneration and risk factors for cataract formation. Moreover, the effects of dietary supplements in the progression of macular disease and cataract formation will be assessed. The prospective nature of this study, its focus on the progression of drusen pathology, and its evaluation of the effects of dietary supplements make this a unique and much needed study.

这项研究的目的是老年相关眼病研究(AREDS)， 要登记患有轻度到重度玻璃体病理的患者，并且a)遵循 黄斑变性的自然进展；以及b)决定饮食是否 复合维生素、矿物质(S)或复合维生素和矿物质的补充剂 延缓疾病的发展。因为登记的患者将不会 有光学上显著的镜片混浊，这项研究还将提供 黄斑患者发生白内障的信息 疾病。这项研究将提供有关进展的新信息 黄斑变性和白内障形成的危险因素。此外， 膳食补充剂在黄斑疾病进展中的作用 并对白内障的形成进行评估。这件事的前瞻性 玻璃体病变的研究、进展及其评价 膳食补充剂的效果使其成为一种独特而迫切需要的 学习。