CEREBRAL MRI TO THE ATHEROSCLEROSIS RISK

本合同的目的是提供阅读服务 中心解释执行的脑磁共振图像(MRI) 流行病学研究中的主要致病因素 对中年人心血管疾病发生的影响 题为“社区动脉粥样硬化风险研究(ARIC)”。核磁共振 阅读中心将协助制定演出协议 对两个ARIC野战中心的2,000名参与者进行了脑MRI检查 位于密西西比州杰克逊市和北卡罗来纳州福赛斯县；将演出 这些图像的测量和解释以标准化和 可复制的方式。 社区动脉粥样硬化风险(ARIC)，一项关于心血管的研究 在美国的四个社区中，男性、女性、黑人和白人之间的疾病， 有两个主要目标：(1)调查与 动脉粥样硬化和临床心血管疾病的发病率， 和(2)测量冠心病(CHD)的发生和趋势并 将它们与社区层面的风险因素、医疗保健和 动脉硬化。在操作上，这项研究包括对 四个社区35岁至74岁所有居民的冠心病 首次检查时对4,000名45岁人群的随访-- (发生在1987-1990年)被选为代表每个社区。这个 学习社区有福赛斯县、北卡罗来纳州、杰克逊、 密西西比州，明尼阿波利斯，明尼苏达州和华盛顿县的郊区， 马里兰州。

The purpose of this contract is to provide the services of a reading center to interpret cerebral magnetic resonance images (MRI) performed in the epidemiological research study of the major factors contributing to the occurrence of cardiovascular disease in middle-aged adults entitled "Atherosclerosis Risk in Communities Study (ARIC)." The MRI Reading Center will assist in protocol development for the performance of cerebral MRI on 2,000 participants at two of the ARIC Field Centers located in Jackson, Ms and Forsyth County, NC; and will perform measurements and interpretations of these images in a standardized and reproducible manner. Atherosclerosis Risk in Communities (ARIC), a study of cardiovascular diseases in four U.S. communities among men, women, blacks and whites, has two primary objectives: (1) to investigate factors associated with both atherosclerosis and incidence of clinical cardiovascular diseases, and (2) to measure coronary heart disease (CHD) occurrence and trends and relate them to community levels of risk factors, medical care and atherosclerosis. Operationally, the study includes both surveillance for coronary disease among all residents aged 35-74 of the four communities and follow-up of cohorts of 4,000 persons aged 45-64 at first examination (which occurred in 1987-1990) selected to represent each community. The study communities are Forsyth County, North Carolina, Jackson, Mississippi, suburbs of Minneapolis, Minnesota, and Washington County, Maryland.