Web Connected Platform for Capturing COVID-19 Rapid Test Data to Support Decision-Makers in Real-Time

用于捕获 COVID-19 快速测试数据以实时支持决策者的网络连接平台

基本信息

  • 批准号:
    62887
  • 负责人:
  • 金额:
    $ 9.53万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Feasibility Studies
  • 财政年份:
    2020
  • 资助国家:
    英国
  • 起止时间:
    2020 至 无数据
  • 项目状态:
    已结题

项目摘要

Accurate, real-time data is essential in the ongoing fight against the coronavirus. Diagnostic testing is being held up as the key to understanding and slowing the spread of the virus. The approach has already had an impact in some countries during this outbreak and was endorsed by the WHO director-general, who urged countries to ramp up testing activity.Similar to governments across the globe, the UK Government is buying huge quantities of rapid tests. Just like police drug tests, they give quick results and are highly accurate, affordable and portable, making them the obvious choice for mass population testing. They are much more fit for this purpose unlike the current frontline standard - the laboratory PCR test - which may be accurate but doesn't offer the turnaround time needed to combat a pandemic.The latest generation of rapid diagnostic tests generate data which reveals valuable information about how the virus is spreading and allows authorities to predict future spread. Using this data, governments can take informed steps to action targeted interventions and protect public health.Rapid tests provide accurate, lab-grade results at the point of testing. However, results can't always be read by the naked eye, so interpreting them is done either via portable, optical reader devices or smartphone readers, which utilise the phone's camera technology. This also mitigates the issues with misinterpretation.**However, the data these diagnostic devices generate is not being captured and used to its full advantage.**Our project is addressing this gap by providing the web platform and technology needed to connect these devices to the internet. Data is captured at the point of testing, stored and aggregated in the cloud where algorithms can be introduced to analyse it. It is instantly visualised on dashboards for decision-makers in real-time.Additional data such as gender, age, underlying health conditions, blood type, and location will be collected, giving richer insight into epidemiology. Geo-tagged results and data trends will be made available on heat maps in the dashboard. This will allow the NHS, public health bodies and other stakeholders to monitor emerging hot spots, enhance response times and allocate resources.This is a completely novel approach. There are several projects around data capture but none of the proposed solutions integrate with an accurate, rapid diagnostic test. Our solution will not only help contain the coronavirus but ultimately eradicate it- and when fully deployed - prevent future waves of the pandemic.The proposed extensions and added value are:1. To develop an additional API (application programming interface) to enable interoperability between our system TRANSFORM and various electronic patient data systems in the UK and the US. In the UK, NHS Digital is moving towards the adoption of interoperable Electronic Patient Record (EPR) system to facilitate better patient data access. Data is collected from systems such as TRANSFORM, so smooth integration and communication between the systems is essential. This represents added value for both the UK public and UK Public Health agencies because the datasets will be much more comprehensive, including additional layers of accurate test, subject, symptom, location and environmental data. This is pretty much all the data public health bodies need in order to make informed decisions fast.2. To extend the functionality of TRANSFORM to incorporate additional comorbidity coding to the records generated for each subject (patient) who using the system to collect data from the rapid lateral flow tests. The comorbidity coding is achieved using internationally recognised standards: SNOMED, and LOINC. These standards are universal and recognised in UK/EU/USA and are used to provide an interoperable medical condition and co-morbidity metadata set for each patient.Both these extended deliverables will enhance the functionality and value of our project in the mid term.
准确、实时的数据对于正在进行的抗击冠状病毒至关重要。诊断性检测被认为是了解和减缓病毒传播的关键。在这次疫情爆发期间,这种方法已经在一些国家产生了影响,并得到了世卫组织总干事的支持,他敦促各国加大检测活动。与全球各国政府类似,英国政府正在购买大量的快速检测。就像警方的毒品测试一样,它们快速得出结果,而且非常准确,负担得起,携带方便,使它们成为大规模人口测试的明显选择。与目前的一线标准-实验室PCR检测-不同,它们更适合于这一目的。目前的一线标准可能是准确的,但不能提供抗击疫情所需的周转时间。最新一代的快速诊断测试产生的数据揭示了病毒如何传播的宝贵信息,并使当局能够预测未来的传播。利用这些数据,政府可以采取明智的步骤,采取有针对性的干预措施,保护公众健康。快速检测在检测时提供准确的实验室级结果。然而,结果并不总是能用肉眼阅读,所以解读结果要么通过便携式光学阅读器,要么通过智能手机阅读器,后者利用了手机的摄像头技术。这也缓解了误解带来的问题。**然而,这些诊断设备生成的数据没有被捕获并充分利用。**我们的项目正在通过提供将这些设备连接到互联网所需的网络平台和技术来解决这一差距。数据在测试点捕获、存储并聚合在云中,在云中可以引入算法来分析数据。它将被实时显示在仪表板上,供决策者使用。还将收集其他数据,如性别、年龄、潜在健康状况、血型和地点,从而对流行病学有更丰富的了解。地理标记的结果和数据趋势将在仪表板的热图上提供。这将使NHS、公共卫生机构和其他利益相关者能够监测新出现的热点,提高反应时间并分配资源。这是一种全新的方法。围绕数据捕获有几个项目,但建议的解决方案中没有一个与准确、快速的诊断测试相集成。我们的解决方案不仅有助于遏制冠状病毒,而且最终将其根除-当全面部署后-防止未来的混乱浪潮。建议的扩展和增值是:1.开发额外的API(应用程序编程接口),以实现我们的系统转换与英国和美国的各种电子患者数据系统之间的互操作性。在英国,NHS Digital正朝着采用可互操作的电子病历(EPR)系统的方向发展,以促进更好的患者数据访问。数据是从Transform等系统收集的,因此系统之间的顺利集成和通信至关重要。这对英国公共卫生机构和英国公共卫生机构都具有附加值,因为数据集将更加全面,包括更多准确的测试、对象、症状、位置和环境数据。这几乎是公共卫生机构迅速做出知情决定所需的全部数据。扩展Transform的功能,将附加的共病编码合并到为使用该系统从快速侧向血流测试中收集数据的每个受试者(患者)生成的记录中。共病编码是使用国际公认的标准实现的:SNOMED和LOINC。这些标准在英国/欧盟/美国是通用的和公认的,用于为每个患者提供可互操作的医疗条件和共同发病元数据集。这两个扩展交付项将在中期增强我们项目的功能和价值。

项目成果

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其他文献

Internet-administered, low-intensity cognitive behavioral therapy for parents of children treated for cancer: A feasibility trial (ENGAGE).
针对癌症儿童父母的互联网管理、低强度认知行为疗法:可行性试验 (ENGAGE)。
  • DOI:
    10.1002/cam4.5377
  • 发表时间:
    2023-03
  • 期刊:
  • 影响因子:
    4
  • 作者:
  • 通讯作者:
Differences in child and adolescent exposure to unhealthy food and beverage advertising on television in a self-regulatory environment.
在自我监管的环境中,儿童和青少年在电视上接触不健康食品和饮料广告的情况存在差异。
  • DOI:
    10.1186/s12889-023-15027-w
  • 发表时间:
    2023-03-23
  • 期刊:
  • 影响因子:
    4.5
  • 作者:
  • 通讯作者:
The association between rheumatoid arthritis and reduced estimated cardiorespiratory fitness is mediated by physical symptoms and negative emotions: a cross-sectional study.
类风湿性关节炎与估计心肺健康降低之间的关联是由身体症状和负面情绪介导的:一项横断面研究。
  • DOI:
    10.1007/s10067-023-06584-x
  • 发表时间:
    2023-07
  • 期刊:
  • 影响因子:
    3.4
  • 作者:
  • 通讯作者:
ElasticBLAST: accelerating sequence search via cloud computing.
ElasticBLAST:通过云计算加速序列搜索。
  • DOI:
    10.1186/s12859-023-05245-9
  • 发表时间:
    2023-03-26
  • 期刊:
  • 影响因子:
    3
  • 作者:
  • 通讯作者:
Amplified EQCM-D detection of extracellular vesicles using 2D gold nanostructured arrays fabricated by block copolymer self-assembly.
使用通过嵌段共聚物自组装制造的 2D 金纳米结构阵列放大 EQCM-D 检测细胞外囊泡。
  • DOI:
    10.1039/d2nh00424k
  • 发表时间:
    2023-03-27
  • 期刊:
  • 影响因子:
    9.7
  • 作者:
  • 通讯作者:

的其他文献

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{{ truncateString('', 18)}}的其他基金

An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
  • 批准号:
    2901954
  • 财政年份:
    2028
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
利用人类肠道微生物群的多糖分解能力来开发环境可持续的洗碗解决方案
  • 批准号:
    2896097
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
  • 批准号:
    2780268
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
  • 批准号:
    2908918
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
  • 批准号:
    2908693
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
  • 批准号:
    2908917
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
  • 批准号:
    2879438
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
  • 批准号:
    2890513
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
CDT year 1 so TBC in Oct 2024
CDT 第 1 年,预计 2024 年 10 月
  • 批准号:
    2879865
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
  • 批准号:
    2876993
  • 财政年份:
    2027
  • 资助金额:
    $ 9.53万
  • 项目类别:
    Studentship

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