Smart affinity membranes for manufacture of high value therapeutic proteins

用于制造高价值治疗性蛋白质的智能亲和膜

• 批准号: LP180100486
• 负责人: Prof Kristofer Thurecht
• 金额: $ 27.38万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-11-06 至 2022-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP180100486
• 关键词: Smart; affinity; membranes; manufacture; value

This project aims to develop next generation separation membranes for production of high-value proteins from serum. Through a combination of innovative chemistries, biotechnology and engineering, the project will enhance production, efficiency and resolution of membranes for separating complex mixtures, thereby contributing to broader understanding in membrane science. By establishing a strong collaborative link between academic and industry researchers, this project has the potential to significantly value-add to existing and exciting Australian technology by enhancing the efficiency of plasma fractionation, improving isolation of large molecules from complex media and by improving the downstream manufacturing and bioprocessing pipeline.

该项目旨在开发新一代分离膜，用于从血清中生产高价值蛋白质。通过结合创新的化学、生物技术和工程学，该项目将提高用于分离复杂混合物的膜的产量、效率和分辨率，从而有助于更广泛地了解膜科学。通过在学术和行业研究人员之间建立强大的合作联系，该项目有可能通过提高等离子体分离的效率、改进从复杂介质中分离大分子以及改善下游制造和生物处理管道，显著增加现有和令人兴奋的澳大利亚技术的价值。