Next generation hybrid nanomaterials: bispecific antibody-targeted polymers
Next generation hybrid nanomaterials: bispecific antibody-targeted polymers
批准号:
LP150100703
负责人:
Prof Kristofer Thurecht
金额:
$25.03万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-06-29 至 2019-06-28
中文摘要
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英文摘要
This project aims to develop and optimise a novel platform technology that will assist in the development of hybrid materials consisting of nanomaterials and biomolecules, which form the basis of many commercial diagnostic devices. A novel antibody, MIL38, will provide the test bed for the technology, which will aim to deliver a platform that is stable under physiological conditions and that enables facile conjugation of nanomaterials with antibodies. This project has the potential to rapidly improve the ligation process between synthetic nanomaterials and biologics, leading to more efficient synthesis of targeted diagnostics. This would provide a significant commercial advantage for any nanomaterials developed for the field, and specifically for this project, expedite translation of MIL38.
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