1997 GORDON CONFERENCE ON ELASTIN AND ELASTIC TISSUE

1997 年戈登弹性蛋白和弹性组织会议

• 批准号: 2371129
• 负责人: WILLIAM C PARKS
• 金额: $ 1.87万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-10 至 1998-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2371129
• 关键词: elastic tissue; elastin; meeting /conference /symposium

DESCRIPTION (Adapted from applicant's abstract and specific aims): This application seeks funding for support of the Tenth Gordon Conference on Elastin and Elastic Tissue to be held at Kimball Union Academy in Meriden, New Hampshire, from July 20-25, 1997. Elastin is a major structural protein of the body, providing extensibility and elastic recoil to the tissues in which it is found. Microfibrils are polymers of distinct glycoproteins. Because of the crucial contribution to the physical and physiological functions of many tissues, alterations in elastin and microfibrillar genes, synthesis, assembly, and repair lead to or are associated with several diseases of major social significance, including Marfan's Syndrome, aneurysms, emphysema, pulmonary and systemic hypertension, arteriosclerosis, and numerous skin conditions, such as elastosis and cutis laxa. The conference will integrate new information on the molecular and cellular biology of these proteins with an emphasis on studies directed at defining the function and interaction of these matrix components. The proposed meeting will bring together basic scientists from a variety of different disciplines to present and discuss the most recent information on elastin and microfibril proteins. As in past years, these interactions will result in new collaborative studies that stimulate novel avenues of investigation of these important connective tissue proteins.

描述(根据申请者的抽象和具体目标改编)：此 申请资助第十届戈登会议 弹性蛋白和弹性组织将在梅里登的金博尔联合学院举行， 新汉普郡，从1997年7月20日至25日。弹性蛋白是一种主要的结构蛋白 为人体组织提供延伸性和弹性回弹力 它就是被发现的。微纤维是由不同的糖蛋白组成的聚合物。 因为对生理和生理的重要贡献 许多组织的功能，弹性蛋白和微纤维基因的变化， 合成、组装和修复导致或与几个 具有重大社会意义的疾病，包括马凡氏综合症， 动脉瘤，肺气肿，肺和全身高血压，动脉硬化， 以及许多皮肤状况，如弹力增生症和皮肤松弛。这个 会议将整合关于分子和细胞的新信息 这些蛋白质的生物学，重点是针对确定 这些基质成分的功能和相互作用。建议数 会议将汇聚来自不同领域的基础科学家 介绍和讨论有关弹性蛋白的最新信息的学科 和微原纤维蛋白。与过去几年一样，这些互动将导致 在新的合作研究中，激发了新的调查途径 这些重要的结缔组织蛋白。