Nunabio: Providing DNA Solutions

Nunabio：提供 DNA 解决方案

• 批准号: 68256
• 金额: $ 26.69万
• 依托单位: NUNABIO LIMITED
• 依托单位国家: 英国
• 项目类别: Study
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=68256
• 关键词: Nunabio; Providing; DNA; Solutions

Biological matter can be precisely identified by the base sequence of its DNA. DNA detection is therefore of global interest where biological contamination is harmful to human health -- water that contains microbial infections, air samples that convey disease, water or food that is contaminated, weapons that disperse biological agents or genetic mutations that lead to the onset of disease.DNA sensors are already utilised in a large number of commercially important market sectors including clinical molecular diagnostics, pathogen detection in food and water and biothreats to homeland security.The current approach to DNA detection can be achieved by two methods including;1\. NGS technologies which provide highly accurate results, however, they can be costly in terms of time, expertise and finances.2\. Point-of-use devices which provide more affordable and rapid time-to-result, but with the drawback of a lower confidence in the automated result.There is motivation within diagnostic companies to move from NGS technologies to point-of-care devices, however, there is an urgent need to improve the confidence in these results.Our patented technology will enable the achievement of the higher confidence levels that are required to make quicker and better-informed decisions and subsequently improve user experience and feedback.Following market research, we found our technology to be applicable within in a number of microbiological testing market sectors including, molecular diagnostics, food and water safety, and biothreat and security.As a first route to market, we identified a pressing unmet need in the water testing market. There is currently no rapid, reliable water quality test available (UNICEF).At Nunabio Ltd, our approach is to work with a global leader in water testing analysis, Palintest Ltd., in a joint-venture that will embed our patented technology into a testing platform that meets industrial requirements.This Innovate UK funding will enable Nunabio Ltd. to set up as a technology development house, recruit new team members, develop and exploit current and new intellectual property in a comprehensive IP strategy to primarily impact the microbial source tracking in water. Accelerating the company development will attract further licencing opportunities of our technology into markets beyond water analysis.

生物物质可以通过其DNA的碱基序列来精确地识别。因此，在生物污染对人类健康有害的地方，DNA检测是全球关注的问题--含有微生物感染的水、传播疾病的空气样本、受污染的水或食物、驱散生物制剂的武器或导致疾病发生的基因突变。DNA传感器已被用于大量具有商业重要性的市场部门，包括临床分子诊断、食品和水中的病原体检测以及国土安全的生物治疗。目前的DNA检测方法可通过两种方法实现，包括：1然而，提供高度准确结果的NGS技术在时间、专业知识和资金方面可能代价高昂。使用点设备，提供更实惠和快速的结果时间，但缺点是对自动结果的置信度较低。诊断公司内部有动机从NGS技术转移到护理点设备，但迫切需要提高对这些结果的信心。我们的专利技术将使我们能够实现更高的置信度，这是做出更快和更知情的决定所需的，并随后改善用户体验和反馈。经过市场研究，我们发现我们的技术适用于许多微生物检测市场部门，包括分子诊断、食品和水安全、作为进入市场的第一条途径，我们发现了水检测市场一个迫切的未得到满足的需求。目前还没有快速、可靠的水质测试(联合国儿童基金会)。在Nunabio Ltd，我们的方法是与水质测试分析领域的全球领先企业Palintest Ltd.合作，成立一家合资企业，将我们的专利技术嵌入到一个满足工业要求的测试平台中。这笔创新英国资金将使Nunabio Ltd.能够建立一个技术开发机构，招募新的团队成员，开发和利用全面知识产权战略中的现有和新知识产权，主要影响水中微生物来源的追踪。加快公司发展将吸引我们的技术进入水分析以外的市场的更多许可机会。