WANDERING AND ITS SEQUELAE--COGNITION AND AGITATION

徘徊及其后遗症——认知与躁动

• 批准号: 2001493
• 负责人: Donna L. Algase
• 金额: $ 24.94万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-04-10 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2001493
• 关键词: behavioral /social science research tag; clinical research; cognition disorders; compulsive behavior; exploratory behavior; human subject; monitoring device; neuropsychological tests; socioenvironment

As an extension of current work, the goals of this study are to further improve the measurement strategy for wandering behavior and to extend the study of wandering in the context of rhythm theory. Level and type of cognitive impairment and agitation, viewed an endogenous pacers, are examined for their impact on wandering. Falls and elopements, outcomes of disrupted wandering rhythm, are also examined. Four biomechanical devices assessing activity are evaluated for their ability to substitute for direct observation in estimating wandering behavior. Using measures indicating level of cognitive impairment (Mini-Mental State Exam; Mattis Dementia Rating Scale; Reisberg Global Deterioration Scale; Test for Severe Impairment) and other instruments assessing the relative severity of right vs left hemispheric damage (Bloomer Block Assessment Protocol; Benton Visual Retention Test; Block Design and Object Assembly sub-tests of the Wechsler Adult Intelligence Scale-Revised), cognitive impairment is examined for its influence on variations in the rhythm, patterns, and sequelae of wandering behavior. Using a form of the Cohen-Mansfield Agitation Inventory, agitation status and type (verbal, physical, and physically nonagressive) are examined for influence on the same dependent variables. A descriptive survey design is used to obtain biomechanical measures of activity and to observe, time, and code wandering variables (rhythm, pattern sequelae) twice over two randomly assigned 4-hour time blocks (16 hours total) for each subject. The targeted population will be 268 cognitively impaired nursing home residents from 14 nursing homes.. Each subject will be categorized as to level of cognitive impairment (mild, moderate, severe), dominant impairment type (right vs left hemisphere), severity of agitation status (none through severe), and type of agitation (verbal, physical, physically nonagressive, or mixed), if agitated. Pearson correlates are planned to evaluate biomechanical devices against direct observation of wandering and between each other. Estimates of clinical acceptability will be refined through factors analyses and reliability assessed using Cronback's alpha. Clinical acceptability of devices will be evaluated using ANOVAs. As determined to be appropriate, analysis of variance techniques, logistical regressions and canonical correlation will be used to examine effects of cognition and agitation on wandering rhythm, pattern and sequelae.

作为当前工作的延伸，本研究的目标是进一步 改进游荡行为的测量策略，并扩展 节奏理论背景下的游荡研究。级别和类别 认知障碍和激动，被视为内源性起搏器， 研究它们对流浪的影响。福尔斯和私奔，结果 的破坏游走节奏，也检查。四个生物力学 评估活动的设备被评估其替代的能力 用于直接观察以估计游荡行为。具体保护措施 指示认知损害的水平（简易精神状态检查; Mattis 痴呆评定量表; Reisberg整体恶化量表;痴呆试验 严重损害）和其他评估相对严重程度的工具 右半球与左半球损伤的比较（布卢默区块评估方案; 本顿视觉保持测试;积木设计和物体组装子测试 韦氏成人智力量表修订版），认知障碍 是检查其影响的变化，节奏，模式， 流浪行为的后遗症使用一种形式的科恩-曼斯菲尔德 激动清单、激动状态和类型（言语、身体和 身体无攻击性）的影响进行了检查，对同一依赖 变量描述性调查设计用于获得生物力学 活动的措施，并观察，时间和代码徘徊变量 （节律，模式后遗症）两次，随机分配4小时时间 每名受试者的时间块（共16小时）。目标人群将 来自14个护理机构的268名认知障碍的养老院居民 家..每个受试者将被分类为认知水平 损害（轻度、中度、重度）、显性损害类型（右侧与 左半球）、激越状态的严重程度（无至重度），以及 激越类型（言语、身体、身体无攻击性或混合）， 如果激动的话。Pearson相关系数计划用于评估生物力学 反对直接观察装置之间的徘徊和相互。 临床可接受性的估计值将通过以下因素进行细化 使用Cronback的alpha进行分析和可靠性评估。临床 将使用ANOVA评价器械的可接受性。确定 适当时，方差分析技术、后勤 回归和典型相关将被用来检查的影响， 对游走节律、方式和后遗症的认知和躁动。