High resolution gas chromatography mass spectrometry for metabolic research

用于代谢研究的高分辨率气相色谱质谱法

• 批准号: LE190100017
• 负责人: Prof Rod Peakall
• 金额: $ 32.61万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-04-24 至 2021-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE190100017
• 关键词: resolution; gas; chromatography; mass; spectrometry

This project aims to fill a major gap in Australia's metabolic analytical infrastructure by making available an automated, high-resolution, two-dimensional gas chromatography quadrupole time-of-flight mass spectrometer. In a collaborative effort to build a critical mass of cutting-edge metabolic analytical tools, this is expected to give Australia a world-leading edge in metabolic research. This project will enhance skills and capabilities of the Australian research community to enable the discovery of important biochemicals and molecular mechanisms and provide an unprecedented capacity to resolve complex metabolic samples, study the volatile metabolome, discover valuable new compounds and measure metabolic flows. Outputs are expected to inform the independent development of new technologies, commercial products and services, creating jobs and generating revenue while benefiting the agriculture, health and environmental sectors.

该项目旨在通过提供自动化、高分辨率、二维气相色谱四极杆飞行时间质谱仪，填补澳大利亚代谢分析基础设施的一个主要空白。在建立一个临界质量的尖端代谢分析工具的合作努力中，这有望使澳大利亚在代谢研究方面处于世界领先地位。该项目将提高澳大利亚研究界的技能和能力，以发现重要的生化物质和分子机制，并提供前所未有的能力来解决复杂的代谢样品，研究挥发性代谢组，发现有价值的新化合物和测量代谢流。预计产出将为新技术、商业产品和服务的独立开发提供信息，创造就业机会和创收，同时惠及农业、卫生和环境部门。