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Novel 3D tissue culture device

新型3D组织培养装置

基本信息

批准号：
700452
负责人：
金额：
$ 2.98万
依托单位：
NOVABIOMATRIX LIMITED
依托单位国家：
英国
项目类别：
GRD Proof of Market
财政年份：
2014
资助国家：
英国
起止时间：
2014 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=700452
关键词：
Novel 3D tissue culture device

项目摘要

Cell culture is the process by which living cells are grown in the laboratory, traditionally in media in a Petri dish. Businesses across many sectors (e.g., pharmaceutical, cosmetics and chemicals) utilise these cultures to test the toxicological effects of new products on living tissue without using animal testing, but these effects are constrained by the 2D (two dimensional) surface provided by media in a plate. There is increasing demand to develop 3D cell culture technologies that can better simulate the cellular environment of the living body in the laboratory. These technologies will lead to greater understanding of human biology therefore reducing development time and research costs for new products to reach the market and potentially becoming a useful tool in the field of regenerative medicine. Existing technology for 3D cell culture is expensive, difficult to use and not easily adaptable for different experiments and cell types. Novabiomatrix Ltd has begun to develop a 3D cell culture methodology that simulates human organ cells in its research labs which it hopes will ultimately not only minimize the need for animal tests but accelerate effective research and development of novel applications. The objective of this application is to assess the market potential of this newly developed patent pending device. This technology will provide a reliable, fast and cost effective device that could be used worldwide in scientific labs with potential to become a standard method.

细胞培养是活细胞在实验室中生长的过程，传统上是在培养皿中的培养基中。许多行业的企业（例如，目前，生物技术（例如，制药、化妆品和化学品）利用这些培养物来测试新产品对活组织的毒理学效应，而不使用动物试验，但这些效应受到平板中培养基提供的2D（二维）表面的限制。人们对开发3D细胞培养技术的需求越来越大，这些技术可以在实验室中更好地模拟活体的细胞环境。这些技术将使人们更好地了解人类生物学，从而减少新产品进入市场的开发时间和研究成本，并可能成为再生医学领域的有用工具。现有的3D细胞培养技术昂贵，难以使用，并且不容易适应不同的实验和细胞类型。Novabiomatrix Ltd已经开始开发一种3D细胞培养方法，在其研究实验室中模拟人体器官细胞，希望最终不仅能最大限度地减少动物试验的需要，还能加速新应用的有效研究和开发。本申请的目的是评估这种新开发的专利申请中的设备的市场潜力。这项技术将提供一种可靠、快速和具有成本效益的设备，可以在世界范围内的科学实验室中使用，并有可能成为标准方法。