CHILD DISRUPTIVE/MOOD DISORDERS DIAGNOSIS

描述(改编自申请人的摘要)：这是第二个 288-6-3期前瞻性纵向研究的阶段 10岁的捣乱和/或抑郁的男孩。该委员会的总体目标 研究是：扩展儿童破坏性精神病理学的双因素模型 抑郁或情绪化的第三个因素；来验证这一扩展 三因素模型，使用收敛和发散有效的直接度量 三个因素(即多动症、攻击性和情绪性)； 将扩展的三因素模型与DSM模型的几个阶段进行比较； 以提高对患者内部和患者之间共病的了解 扰乱性/抑郁障碍；开发和测试组合的方法 将数据转化为合理的诊断决策；并为 对破坏性障碍和抑郁障碍进行细分。 被推荐的男孩有八个亚组：(1)独有的多动症= H；(2)完全具有攻击性=A；(3)完全情绪化=E；(4) 过度活跃和攻击性组合=HA；(5)组合过度活跃和攻击性 情绪化=HE；(6)攻击性和情绪化相结合=AE；(7)混合 过度活跃、攻击性和情绪化=HAE；以及(8)既不过度活跃 既不具有攻击性，也不情绪化=精神控制或PC，以及144 同学控制或抄送。 外部验证的依赖标准包括：描述性 变量(例如，发病年龄、损害程度)；家庭变量 (例如，家庭组成、父母教养方式、婚姻和谐)；认知和 神经心理测量(例如，智力功能、学术 技能，CPT)；观察性测量(例如，游戏和任务中的行为 环境、亲子交互)；个性测量(例如， 自我概念、感觉寻求、社会认知和归因)； 代际指数(例如，一级中的维度和障碍 亲属)；病程(精神症状/行为维度 从11岁到16岁)；和一般结果(精神、认知、 16岁时的学业、社交和行为状况)。 这一调查的第二阶段将包括兄弟姐妹风险 组件，使用关于100个6岁到10岁的 目前的样本男孩回答有关表情，诊断， 和发展的破坏性和抑郁症状和障碍 女孩们。

DESCRIPTION (Adapted from the applicant's abstract): This is the second phase of a three-phase prospective longitudinal study of 288 6- through 10-year-old disruptive and/or depressive boys. The general aims of the study are: to extend a two-factor model of child disruptive psychopathology to a third factor of depression or emotionality; to validate that extended three-factor model, using convergently and divergently valid direct measures of the three factors (i.e., hyperactivity, aggression, and emotionality); to compare the extended three-factor model to several stages of the DSM model; to improve understanding of comorbidity within and between the disruptive/depressive disorders; to develop and test methods for combining data into sound diagnostic decisions; and to make a unified proposal for subgrouping the disruptive and depressive disorders. There are eight subgroups of referred boys: (1) exclusively hyperactive = H; (2) exclusively aggressive = A; (3) exclusively emotional = E; (4) combined hyperactive and aggressive = HA; (5) combined hyperactive and emotional = HE; (6) combined aggressive and emotional = AE; (7) mixed hyperactive and aggressive and emotional = HAE; and (8) neither hyperactive nor aggressive nor emotional = psychiatric controls or PC, as well as 144 classmate controls or CC. The dependent criteria for external validation include: descriptive variables (e.g., age of onset, degree of impairment); family variables (e.g., family composition, parenting styles, marital harmony); cognitive and neuropsychological measures (e.g., intellectual functioning, academic skills, CPT); observational measures (e.g., behavior in play and task settings, parent-child interactions); personality measures (e.g., self-concept, sensation seeking, social cognition and attribution); generational indices (e.g., dimensions and disorders in first-degree relatives); course of symptoms (psychiatric symptoms/behavioral dimensions traced from ages 11 to 16); and general outcomes (psychiatric, cognitive, academic, social, and behavioral status at age 16). This second phase of the investigation will incorporate a sibling risk component, using information about 100 6- through 10-year-old sisters of the present sample of boys to answer questions about the expression, diagnosis, and development of disruptive and depressive symptoms and disorders in girls.