CONSEQUENCES OF COMORBID DRUG ABUSE AND MENTAL DISORDERS

共病药物滥用和精神障碍的后果

• 批准号: 2408729
• 负责人: Barbara E Havassy
• 金额: $ 43.88万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2002-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2408729
• 关键词: alcoholism /alcohol abuse; behavioral /social science research tag; clinical research; comorbidity; crime victims; disease /disorder proneness /risk; drug abuse; health care cost /financing; health care service utilization; health services research tag; human subject; interview; longitudinal human study; mental health epidemiology; mental health services; psychosocial service; quality of life; violence

DESCRIPTION: (Applicant's Abstract) This proposal concerns the impact of comorbid drug abuse and mental disorders on individuals and service systems. Using a longitudinal design, this study will contrast two samples of comorbid adults recruited during an acute care episode in county service systems. One sample will be drawn from the substance abuse treatment system (n=125), and one will be drawn from the mental health treatment system (n=125). To control for differences not related to comorbidity, an equal number of non-comorbid subjects will be recruited, bringing the sample total to 500 subjects, 250 from substance abuse and 250 from mental health treatment. Data on key demographic and severity of alcohol and drug use variables will be obtained at treatment entry, and a diagnostic assessment will be performed. Psychosocial data on alcohol and drug use, risk factors for HIV/AIDS, prevalence of violence, and quality of life will be obtained for a prospective 24 month community follow-up period. Service use and cost data will be obtained from substance abuse, mental health, public health, and forensic services for a period of 24 months prospectively and 24 months retrospectively from time of recruitment. We will test the null hypothesis that the two samples are from the same population on key entry variables. The samples will also be contrasted on the psychosocial, service use, and cost variables. If the samples are found to be from the same population on key entry variables, then differences in psychosocial status, service use, and costs will suggest differences in treatment service systems rather than differences between the clients of these systems. If the samples are significantly different on key entry variables, it will imply the presence of unique comorbid groups. Both similarities and differences between the two samples will be of utmost value. Findings that the comorbid samples are from the same population can guide coordination or integration of services. Findings that they are from different populations can lead to increased precision in distinguishing types of comorbid disorders in treatment systems and should enhance development of services, tailored to the needs of unique comorbid groups.

描述：(申请人摘要) 这项提议涉及到药物滥用和精神疾病的共同影响。 对个人和服务系统的障碍。采用纵向设计， 这项研究将对比两个共病成年人的样本，这些成年人是在 县级服务系统中的急性护理事件。一份样本将从 药物滥用治疗系统(n=125)，其中一项将从 心理健康治疗系统(n=125)。控制差异不是 与合并症相关的非合并症受试者数量相等 招聘，使样本总数达到500名受试者，其中250人是实质性的 另有250人来自精神健康治疗。主要人口统计数据和 酒精和药物使用的严重程度变量将在治疗时获得 输入，并将执行诊断评估。心理社会数据 酒精和毒品的使用、艾滋病毒/艾滋病的危险因素、暴力的流行以及 未来24个月的社区将获得生活质量 随访期。服务使用和成本数据将从物质中获取 虐待、精神健康、公共卫生和法医服务 前瞻性24个月和回溯性24个月 招聘。我们将检验两个样本来自的零假设 关键条目变量的总体相同。样品也将是 在心理社会、服务使用和成本变量上进行对比。如果 在关键条目变量上发现样本来自相同的总体， 然后，心理社会状况、服务使用和成本方面的差异将表明 治疗服务系统的差异，而不是 这些系统的客户端。如果样本在键上有显著不同 进入变量，这将意味着存在独特的共病群体。两者都有 这两个样品的相似之处和不同之处是最大的。 价值。共病样本来自同一人群的研究结果可能 指导服务的协调或整合。他们的发现来自于 不同的种群可以提高区分的精度 治疗系统中的共病类型，应加强 发展服务，为独特的共生群体的需求量身定制。