DEVELOPMENTAL STUDIES ON TREATMENT OF COMPLEX PATIENTS

中心应用程序的这一发展组成部分延续了中心的传统，即支持培训和指导，以提高中心调查人员中经验不足的研究人员的技能，并促进他们作为药物滥用研究人员的职业生涯。它提供了一个统一的结构，中心的高级研究人员可以继续成功地指导和发展更多的初级同事，从而使中心和外地受益。我们建议促进高级研究培训，以培养初级研究人员和博士后学员的强烈研究身份，并培养高级和初级研究人员之间的动态交流。这些科学活动是该中心的重要组成部分。这一部分的具体目标是：（1）为从事药物滥用治疗和服务研究的博士后学员和初级调查员管理一个竞争性的试点研究方案;（2）为博士后学员和新的调查员提供高级研究培训的指导和教学机会;（3）支持真相与和解委员会新调查员的发展研究，从而导致R 01的应用。试点研究计划由PI组件Havassy博士领导，将包括严格审查和资助博士后学员的试点研究，研究将使R 01的开发成为可能，并有望产生出版的手稿。每个项目年度将资助两项试验研究，每项研究的最高资助额为10，000美元。高级培训也将反映在一个先进的方法研讨会，由PI和中心PI，霍尔博士领导。该研讨会旨在巩固经验不足的研究人员的技能和研究经验，重点是设计具有科学完整性和内部和外部有效性的严格研究。在这一部分的主持下，总共将启动四项发展研究提案;两项在中心资助期的上半年进行，两项在下半年进行。提案将符合与科学卓越有关的具体标准，并将继续强调中心对复杂患者的药物滥用治疗。中心高级 研究人员，哈瓦西，霍尔，索伦森，韦尔舍和盖迪什博士，将为准备这些研究的研究人员提供咨询。将对研究摘要进行审查，并邀请最有希望的人提交一份发展研究的提案。这些将被审查的科学价值，一旦批准的资金将被发送到NIDA中心的项目官员批准。

This developmental component of the Center application continues the Center tradition of supporting training and mentoring to enhance the skills of less experienced researchers among Center investigators and to further their careers as drug abuse researchers. It provides a unifying structure around with Center senior investigators can continue their successful mentoring and development of more junior colleagues, thus benefiting the Center and the field. We propose to promote advanced research training to foster development of strong research identities among junior investigators and post-doctoral trainees, and to cultivate a dynamic interchange between senior and junior investigators. These scientific activities are crucial elements of the Center. Specific aims of this component are: (1) administer a competitive pilot study program for post-doctoral trainees and junior investigators who are working in drug abuse treatment and services research; (2) provide direction and didactic opportunities for advanced research training for post-doctoral trainees and newer investigators; and (3) support developmental research of TRC new investigators leading to R01 applications. The pilot studies program, lead by the component PI, Dr. Havassy, will consist of stringent review and funding of pilot research of post-doctoral trainees, research that will enable development of a R01 and that has the promise of resulting in a published manuscript. Two pilot studies will be funded each project year and the maximum funding is $10,000 per study. The advanced training will also be reflected in an advanced methods seminar, lead by the PI and the Center PI, Dr. Hall. The seminar is designed to consolidate skills and research experience of less experienced investigators with a focus on design of rigorous studies with scientific integrity and with internal and external validity. Under the auspices of this component, a total of four developmental research proposals will be initiated; two conducted in the first half of the Center funding period and two in the latter half. Proposals will meet specified criteria having to do with scientific excellence and will continue the emphasis of the Center on drug abuse treatment for complex patients. Center senior investigators, Drs. Havassy, Hall, Sorensen, Welsher and Guydish, will provide consultation to the investigators preparing these studies. Study abstracts will be reviewed and the most promising will be invited to submit a proposal for a developmental study. These will be reviewed for scientific merit and once approved for funding will be sent to NIDA Centers project officer for approval.