COCHLEAR MECHANICS

描述：此申请寻求对私家侦探S的持续支持 在BASIC中使用直流敏感激光干涉仪的开创性工作 耳蜗区振动的研究。这三个目标是a) 对覆盖物的振动进行更广泛的表征 耳蜗尖的膜，P.I.在其中描述了 第一次压缩非线性，b)完成一系列广泛的 耳蜗基底膜振动的研究，以及c)开始 耳蜗中转振动模式的研究。在顶端 Cochlea，研究将包括广泛探索 双色调失真产物的生成，一款小但 对覆盖膜振动具有潜在重要意义的直流分量，以及 神经兴奋的响应阶段分析，依赖于神经和 感受器电位记录。总体目标是一个完整的描述，在 所有的旋转，科尔蒂管风琴的振动机械。

DESCRIPTION: This application seeks continuing support for the P.I.'s pioneering work in the use of a DC-sensitive laser interferometer in basic studies of the vibration of the cochlea partition. The three goals are a) to perform more extensive characterization of the vibration of the tectorial membrane in the apical cochlea, in which the P.I. has described for the first time a compressive nonlinearity, b) to complete an extensive series of studies of basilar membrane vibration in the basal cochlea, and c) to begin studies of vibration patterns in the cochlea middle turn. In the apical cochlea, studies will include extensive exploration of the ranges of two-tone distortion product generation, an examination of a small but potentially significant dc component to tectorial membrane vibration, and an analysis of the response phase of neural excitation, relying on neural and receptor potential recording. The overall aim is a complete description, in all turns, of the vibratory mechanics of the organ of Corti.