SINGLE UNIT AND BEHAVIORAL RESPONSES TO ODORANT SERIES

发展对嗅觉信息处理的理解 事实证明，该系统是一项艰巨的任务。关于二者关系的研究 嗅球的生理活动与嗅觉之间的关系 由于缺乏关于香气世界的信息，质量受到了影响 实验动物。这里提出的实验采用了集成的 比较使用单个单位测量的生理活动的方法 记录和气味是由嗅球活动编码的。使用行为 与生理学方法相结合，可以检查具体问题 单独使用这两种方法都不能解决这个问题。该提案涉及 两个具体目标：1)确定气味是否不能 在行为任务中被区别对待会引发类似的活动模式 单个嗅球输出神经元，以及2)确定意义 二尖瓣/簇状细胞群体反应的空间模式 对气味质量进行编码。这些实验的结果将有助于 对理解网络中的信息处理具有重要意义 嗅觉系统。

Developing an understanding of information processing in the olfactory system has proven to be a difficult task. Research on the relationship between physiological activity in olfactory bulb and the perception of odor quality has suffered from a lack of information about the odor world of the experimental animal. The experiments proposed here employ integrated methods to compare physiological activity, measured using single unit recording and odors are coded by olfactory bulb activity. Using behavioral and physiological methods in combination, specific issues can be examined that cannot be addressed using either method alone. The proposal addresses two specific aims: 1) to determine whether odors that cannot be discriminated in a behavioral task elicit similar activity patterns in single olfactory bulb output neurons, and 2) to determine the significance of the spatial patterns of response of populations of mitral/tufted cells in encoding odor quality. The results of these experiments will contribute significantly to the understanding of information processing in the olfactory system.