MUTATION AND RECOMBINATION OF RETROVIRUSES
MUTATION AND RECOMBINATION OF RETROVIRUSES
批准号:
2397406
负责人:
JIAYOU ZHANG
金额:
$10.06万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-08-01 至 2002-07-31
关键词:
DNA directed RNA polymerase DNA replication RNA directed DNA polymerase enzyme activity frameshift mutation genetic recombination human immunodeficiency virus microorganism culture murine leukemia virus nucleic acid sequence nucleic acid structure transfection /expression vector virus DNA virus RNA virus genetics virus replication
中文摘要
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英文摘要
DESCRIPTION: Dr. Zhang proposes to compare the rate of mutation in vivo
during first and second strand DNA synthesis. He will utilize an in vitro
assay to compare the frameshift rates of RNA polymerase II, RT first strand,
and RT second strand synthesis. He will test the three prevailing models
for how recombination occurs in retroviruses using in vivo and in vitro
systems. He will also test the effects of RNA secondary structure on
stimulation of recombination.
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MUTATION AND RECOMBINATION OF RETROVIRUSES
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批准号:6376250
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项目类别:
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资助金额:$10.57万
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财政年份:1997
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负责人:JIAYOU ZHANG
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依托单位:
MUTATION AND RECOMBINATION OF RETROVIRUSES
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批准号:2748853
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项目类别:
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资助金额:$9.87万
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财政年份:1997
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负责人:JIAYOU ZHANG
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依托单位:
MUTATION AND RECOMBINATION OF RETROVIRUSES
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批准号:6173250
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项目类别:
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资助金额:$10.32万
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财政年份:1997
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负责人:JIAYOU ZHANG
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依托单位:
MUTATION AND RECOMBINATION OF RETROVIRUSES
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批准号:2895526
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项目类别:
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资助金额:$10.08万
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财政年份:1997
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负责人:JIAYOU ZHANG
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依托单位:
海外基金