PREPARATION OF RADIOLABELED ANTI-AIDS COMPOUNDS

合成、采购、测试和分发放射性标记材料。是这样的 校内和校外调查人员使用放射性标记材料 用于临床前和临床药理学研究。分配给 放射性标记材料的制备或采购由 项目官员，包括各种化学品和放射性物质 原子，主要强调的是欲望的准备 通过使用14C和氚的合成程序标记材料。 主要的重点将是制备所需的放射性标记 通过合成程序合成化合物，将涉及各种不同的 化合物。所需化合物可能包括一种或多种放射性元素。 合成方法将可用于我的感冒，但不是所有的， 实例。新的和/或现有的合成程序的开发应 必填项。 经营放射性标记药物合成的制备实验室 材料。每年大约5至10种放射性标记制剂应 要预料到。 为以下项目提供放射性标记材料的存储和分发 大约50种化合物。所有货物的重量、包装和标签， 预计每月大约有10批货物出货。

Synthesize, procure, test, and distribute radiolabeled materials. Such radiolabeled materials are used by intramural and extramural investigators for preclinical and clinical pharmacological studies. Assignments for preparation or procurement of radiolabeled materials are made by the Project Officer and include a wide variety of chemicals and radioactive atoms with the major emphasis being on the preparation of the desire labeled materials via synthetic procedure using 14C and tritium. Major emphasis will be on the preparation of the desired radiolabeled compounds via synthetic procedures and will involve a wide variety of compounds. Compounds required may include one or more radioactive elements. Methods of synthesis will be available for "colds runs" in my, but not all, instances. Development of new and/or existing synthetic procedures shall be required. Operate a preparation laboratory for the synthesis of radiolabeled materials. Approximately 5 to 10 radiolabeled preparations per year should be anticipated. Provide storage and distribution of radiolabeled materials for approximately 50 compounds. Weight, package and label all shipments, approximately 10 shipments per month should be anticipated.