Beyond Hendra: the significance of viral communities in bat virus spillover

超越亨德拉：病毒群落在蝙蝠病毒溢出中的重要性

• 批准号: DE190100710
• 负责人: Dr Alison Peel
• 金额: $ 29.67万
• 依托单位: Griffith University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-06-20 至 2024-06-19
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE190100710
• 关键词: Beyond; Hendra; significance; viral; communities

This project aims to address the emerging global health threat posed by zoonotic bat-borne viruses, by determining why bats shed multiple viruses in synchronised pulses. The project expects to identify universal drivers of multi-viral shedding pulses, using Hendra virus as a model system for other bat viruses in Australia and globally. Expected outcomes include insights into the interactions between environmental change, bat ecology, viral dynamics and spillover, prediction of when and where bat viral shedding will most likely occur, and development of new ecological interventions to prevent bat virus spillover in Australia and globally. This will provide significant benefits by pre-empting spillover and global pandemics before they occur.

该项目旨在通过确定蝙蝠在同步脉冲中传播多种病毒的原因，解决由人畜共患蝙蝠传播的病毒对全球健康构成的新威胁。该项目希望利用亨德拉病毒作为澳大利亚和全球其他蝙蝠病毒的模型系统，确定多种病毒脱落脉冲的通用驱动因素。预期成果包括洞察环境变化、蝙蝠生态、病毒动力学和溢出之间的相互作用，预测最有可能发生蝙蝠病毒脱落的时间和地点，以及开发新的生态干预措施，以防止蝙蝠病毒在澳大利亚和全球蔓延。这将通过在溢出和全球大流行发生之前先发制人，提供巨大的好处。