Improving the management of an emerging viral disease in Australia: determination of the mechanisms of neuroinvasion by Hendra virus and their control, leading to optimisation of post-exposure therapy following contact with Hendra virus

改善澳大利亚新出现的病毒性疾病的管理：确定亨德拉病毒的神经侵袭机制及其控制，从而优化与亨德拉病毒接触后的暴露后治疗

• 批准号: nhmrc : 1022516
• 负责人: A/Pr John Stambas
• 金额: $ 45.06万
• 依托单位: CSIRO
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/improving-management-an-hendra-virus/110196
• 关键词: Improving; management; emerging; viral; disease

Hendra virus causes severe disease in people with >50% mortality; human infection is acquired following contact with affected horses. In nature, Hendra virus is carried by flying foxes and the cause of spill-over events to horses is unknown. The impact of Hendra virus on human health may rapidly increase in response to continued urban expansion; the outcome of this project will be improved decision support for those charged with the medical management of people exposed to this deadly virus.

亨德拉病毒导致严重的疾病，死亡率为50%;人类感染是在接触受影响的马匹后获得的。在自然界中，亨德拉病毒是由飞狐携带的，对马的溢出事件的原因尚不清楚。亨德拉病毒对人类健康的影响可能会随着城市的持续扩张而迅速增加;该项目的成果将改善对那些负责接触这种致命病毒的人的医疗管理的决策支持。