课题基金 / 基金详情

GENE DELIVERY OF OP-1 IN RODENT MODEL OF RENAL FIBROSIS

GENE DELIVERY OF OP-1 IN RODENT MODEL OF RENAL FIBROSIS
OP-1 在啮齿动物肾纤维化模型中的基因递送
批准号：
2733945
负责人：
GLENN A MCDONALD
金额：
$1.58万
依托单位：
BETH ISRAEL DEACONESS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
未结题
起止时间：
1998-07-01 至
来源：
https://reporter.nih.gov/project-details/2733945
关键词：
Adenoviridae bone metabolism cystic kidney diabetic nephropathy fibrosis gene expression gene therapy genetic manipulation genetic promoter element histology laboratory mouse molecular cloning nucleic acid sequence osteogenesis serology /serodiagnosis transfection transfection /expression vector urinalysis

项目摘要

项目成果

GLENN A MCDONALD的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The two major goals of this research proposal are the following: to construct an optimal replication deficient adenoviral expression vector; and to evaluate the delivery of a therapeutic protein from this vector in a preclinical model of renal fibrosis. To this end I will utilize sophisticated molecular biological techniques to optimize the construct that I have made and make novel vectors as well. Protein expression will be evaluated in-vivo. After this evaluation is complete I will utilize this vector therapeutically in both a renal ablation and diabetic model of renal fibrosis.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Gene Delivery of OP-1 in Rodent Model of Renal Fibrosis
Gene Delivery of OP-1 in Rodent Model of Renal Fibrosis
GENE DELIVERY OF OP-1 IN RODENT MODEL OF RENAL FIBROSIS
GENE DELIVERY OF OP-1 IN RODENT MODEL OF RENAL FIBROSIS
海外基金