AGGRESSION AND VIOLENCE IN COMMUNITY BASED AD FAMILIES

描述(改编自申请者摘要)：三年的支持是 要求对阿尔茨海默病进行流行病学回顾研究 家庭以确定个人、家庭和互动因素，这些因素 与冲突解决方面的变化有关，包括发展 阿尔茨海默病患者及其家庭的攻击性和暴力行为 为这些人提供照顾的成员。除了描述 这些行为的前置因素和条件，建议的研究 将集中并定义将照顾者和AD放置在 面临更严重形式的暴力行为风险的患者以及 这些因素阻止了更严重的形式的 暴力。 拟议的研究计划有四个具体目标：(1)描述如何 冲突解决方式的变化发生在阿尔茨海默病患者家庭中 阿尔茨海默病的进展；(2)确定各种疾病的具体发生率 冲突解决形式，重点是攻击率， 暴力，严重暴力行为；(3)确定具体患者 和照顾者的特征，使家庭处于攻击性和 暴力；(4)指明倾向于禁止暴力的特征 照顾有家庭成员的家庭发生暴力或攻击行为 广告。 建议项目的患者和护理者将是 从六家由国家资助的记忆障碍诊所征集 佛罗里达州阿尔茨海默病倡议，并将包括所有人(和 指定照顾者)根据NINCDS/ADRDA标准诊断为AD 或诊断为阿尔茨海默型原发性退行性痴呆 根据DSM-III-R或阿尔茨海默病类型的痴呆 DSM-IV或患有混合性AD和血管性痴呆，初步诊断为 广告或混合广告至少在联系前一年进行 学习。1500个家庭的数据将通过邮寄的护理员进行收集 旨在收集家庭基本信息的调查问卷 人口统计学，照顾者扮演照顾者角色的经验，以及 对照顾者行为的看法；2)照顾者面对面 面谈旨在获得有关照顾者的更多信息 包括有关攻击和虐待的敏感信息；以及3)患者 面对面的访谈旨在获得有关患者的信息 自己对他们的攻击和虐待水平的认知 照顾他人的关系。数据分析技术旨在解决 本研究的具体目的。分析方法将包括路径 分析、判别函数分析和多元Logistic回归。 这些技术将使我们能够确定 攻击性和暴力行为的风险和保护因素 照顾阿尔茨海默病患者的家庭。

DESCRIPTION (Adapted from applicant's abstract): Three years of support are requested to conduct an epidemiologic retrospective study of Alzheimer families to identify individual, family and interactive factors that are associated with changes in conflict resolution, including the development of aggressive and violent behavior among individuals with AD, and family members providing care to those persons. In addition to describing antecedent factors and conditions of these behaviors, the proposed research will concentrate and define factors that place both caregivers and AD patients at risk for the more severe forms of violent behavior as well as those factors that prohibit the development of the more severe forms of violence. The proposed research plan has four specific aims: (1) to describe how changes in conflict resolution occur in Alzheimer families with the progression of AD; (2) to determine specific rates of occurrence for various forms of conflict resolution, with an emphasis on the rates of aggressive, violent, and severely violent behavior; (3) to determine specific patient and caregiver characteristics that place families at risk for aggression and violence; (4) to specify characteristics that tend to prohibit the development of violence or aggression in families caring for a member with AD. Patient and caregiver participants for the proposed project will be solicited from six of the Memory Disorder Clinics funded through the State of Florida's Alzheimer Disease Initiative and will include all persons (and designated caregivers) diagnosed with AD according to NINCDS/ADRDA criteria or a diagnosis of Primary Degenerative Dementia of the Alzheimer's Type according to DSM-III-R or Dementia of the Alzheimer's Type according to DSM-IV or with mixed AD and vascular dementia, with an initial diagnosis of AD or mixed AD made at least one year prior to being contacted for the study. Data on 1,500 families will be collected using a 1) Caregiver Mailed Questionnaire designed to collect basic information about the family's demographics, the caregiver's experience with the caregiving role, and perceptions of the care-recipient's behavior; 2) Caregiver Face-to-Face Interview designed to obtain additional information about the caregiver including sensitive information about aggression and abuse; and 3) Patient Face-to-Face Interview designed to obtain information about the patients' own perceptions of their functioning levels of aggression and abuse in the caregiving relationship. Data analytic techniques are designed to address the specific aims of this research. Analytic methods will include path analysis, discriminate function analysis, and multiple logistic regression. These techniques will allow us to determine the characteristics that are both risk and protective factors for aggressive and violent behavior in families caring for members with AD.