AGGRESSION AND VIOLENCE IN COMMUNITY BASED AD FAMILIES

描述（改编自申请人的摘要）：三年的支持是 要求对阿尔茨海默病进行流行病学回顾性研究， 家庭，以确定个人，家庭和互动因素， 与解决冲突方面的变化，包括制定 AD患者和家庭中的攻击性和暴力行为 为这些人提供照顾。 除了描述 这些行为的前因因素和条件，建议的研究 将集中和定义因素，使照顾者和AD 有更严重暴力行为风险的患者， 这些因素，禁止发展的更严重的形式， 暴力 本研究计划有四个具体目标：（1）描述如何 在阿尔茨海默氏症家庭中， AD进展;（2）确定各种疾病的具体发生率 解决冲突的形式，重点是侵略性， 暴力和严重暴力行为;（3）确定特定患者 和照顾者的特点，使家庭处于攻击的风险， （4）具体说明倾向于禁止暴力的特征; 在照顾患有精神分裂症的成员的家庭中发生暴力或攻击行为 AD. 参与拟议项目的患者和护理人员将 从六个由州政府资助的记忆障碍诊所中征求意见， 佛罗里达的阿尔茨海默病倡议，将包括所有人（和 根据NINCDS/ADRDA标准诊断为AD的指定护理人员 或诊断为阿尔茨海默型原发性退行性痴呆 根据DSM-III-R的阿尔茨海默型痴呆或根据 DSM-IV或混合AD和血管性痴呆，初步诊断为 广告或混合广告在联系之前至少一年制作 study. 1,500个家庭的数据将通过以下方式收集： 调查问卷旨在收集家庭的基本信息， 人口统计学，照顾者对照顾角色的经验，以及 对护理接受者行为的感知; 2）护理者面对面 访谈旨在获得有关护理人员的其他信息 包括有关攻击和虐待的敏感信息;以及3）患者 面对面访谈，旨在获得有关患者 他们的侵略和虐待的运作水平的自己的看法， 亲密关系。 数据分析技术旨在解决 这项研究的具体目标。 分析方法将包括路径 判别函数分析和多元逻辑回归。 这些技术将使我们能够确定 攻击性和暴力行为的风险和保护因素， 照顾AD患者的家庭。

DESCRIPTION (Adapted from applicant's abstract): Three years of support are requested to conduct an epidemiologic retrospective study of Alzheimer families to identify individual, family and interactive factors that are associated with changes in conflict resolution, including the development of aggressive and violent behavior among individuals with AD, and family members providing care to those persons. In addition to describing antecedent factors and conditions of these behaviors, the proposed research will concentrate and define factors that place both caregivers and AD patients at risk for the more severe forms of violent behavior as well as those factors that prohibit the development of the more severe forms of violence. The proposed research plan has four specific aims: (1) to describe how changes in conflict resolution occur in Alzheimer families with the progression of AD; (2) to determine specific rates of occurrence for various forms of conflict resolution, with an emphasis on the rates of aggressive, violent, and severely violent behavior; (3) to determine specific patient and caregiver characteristics that place families at risk for aggression and violence; (4) to specify characteristics that tend to prohibit the development of violence or aggression in families caring for a member with AD. Patient and caregiver participants for the proposed project will be solicited from six of the Memory Disorder Clinics funded through the State of Florida's Alzheimer Disease Initiative and will include all persons (and designated caregivers) diagnosed with AD according to NINCDS/ADRDA criteria or a diagnosis of Primary Degenerative Dementia of the Alzheimer's Type according to DSM-III-R or Dementia of the Alzheimer's Type according to DSM-IV or with mixed AD and vascular dementia, with an initial diagnosis of AD or mixed AD made at least one year prior to being contacted for the study. Data on 1,500 families will be collected using a 1) Caregiver Mailed Questionnaire designed to collect basic information about the family's demographics, the caregiver's experience with the caregiving role, and perceptions of the care-recipient's behavior; 2) Caregiver Face-to-Face Interview designed to obtain additional information about the caregiver including sensitive information about aggression and abuse; and 3) Patient Face-to-Face Interview designed to obtain information about the patients' own perceptions of their functioning levels of aggression and abuse in the caregiving relationship. Data analytic techniques are designed to address the specific aims of this research. Analytic methods will include path analysis, discriminate function analysis, and multiple logistic regression. These techniques will allow us to determine the characteristics that are both risk and protective factors for aggressive and violent behavior in families caring for members with AD.