Longitudinal examination of emotional reactivity and reactive aggression linking threat exposure with childhood self-injurious thoughts and behaviors

将威胁暴露与儿童自伤思想和行为联系起来的情绪反应和反应性攻击的纵向检查

• 批准号: 10734437
• 负责人: Adam Bryant Miller
• 金额: $ 84.07万
• 依托单位: RESEARCH TRIANGLE INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10734437
• 关键词: 7 year old; Adolescence; Adolescent; Adolescent Risk Behavior; Adult; Age; Aggressive behavior; Behavior; Caregivers; Catchment Area; Cessation of life; Child; Childhood; Clinical; Communities; Data; Development; Emotional; Enrollment; Event; Exposure to; Feeling suicidal; Female; Future; Goals; Grain; Home; Intervention; Interview; Link; Longevity; Measurement; Mediation; Mental disorders; Methods; Modeling; National Institute of Mental Health; Nursery Schools; Parents; Pathway interactions; Physiological; Prevention; Process; Psychopathology; Questionnaires; Race; Recording of previous events; Recurrence; Research; Risk; Risk Behaviors; Risk Factors; Sampling; School-Age Population; Self-Injurious Behavior; Sex Differences; Sinus; Suicide; Suicide attempt; Testing; Thinking; Time; Translation Process; Work; Youth; aged; behavior measurement; behavior prediction; biological sex; critical period; diaries; experience; follow up assessment; middle childhood; multimodality; non-suicidal self injury; peer; preadolescence; prevent; prospective; psychologic; racial difference; racial diversity; research study; respiratory; response; sex; social; stressor; suicidal morbidity; suicidal risk; suicide rate; theories

PROJECT SUMMARY/ABSTRACT Despite misconceptions that young children do not experience self-injurious thoughts and behaviors (STBs), data from samples of youth that include children under age 9 suggest rates of suicidal ideation between 11%–19%, non-suicidal self-injury at 6.2%–21%, and suicide attempts between 2.4%–3.5%. Although rare, rates of suicide death in young children are increasing. However, the development of STBs in young children is vastly understudied. Our team’s research demonstrates a robust link between threat exposure history and risk for STBs in youth. Moreover, data support that threat experiences increase risk for STBs possibly through heightened emotional reactivity and reactive aggression. Much of the work examining the impact of threat exposure on the development of STBs focuses on adolescent youth, long after many children have experienced threat and after STBs have developed for some youth. The purpose of the current study is to test key components of our conceptual model positing that a history of exposure to threat initiates develop- mental pathways toward earlier risk for STBs in young children through its influence on emotional reactivity and reactive aggression. Moreover, youth may be at greatest risk for STBs in the days after future threat and non-threat negative events occur, highlighting the need to understand potential short-term risk (i.e., over days) for STBs among young children. Aim 1 of this proposal will investigate the extent to which more severe and multiple threat exposures contribute to earlier emergence of STBs in young children ages 5–9. Aim 2 will examine emotional reactivity and reactive aggression as predictors of STBs, including short-term (days) and longer-term (months) predictors, and as mechanisms through which threat may influence STBs. Aim 3 will examine the extent to which future threat and non-threat negative events amplify short- and long-term risk for STBs among young children with emotional reactivity and reactive aggression. We will conduct exploratory analyses testing our full model positing that threat influences STBs through heightened emotional reactivity and reactive aggression, particularly when future threat or non-threat events occur. We will also explore sex and race differences in STBs in young children. We will enroll 300 5- to 7-year-olds with a history of a range of threat exposure and their caregiver in a racially diverse catchment area and follow youth longitudinally for 2 years (until ages 7–9). Youth and caregivers will complete an in-home baseline assessment composed of multiple methods, including clinical interviews; questionnaires; and observational, physiological (i.e., respiratory sinus arrythmia), and behavioral measures within developmentally relevant negative emotional contexts (e.g., social-evaluative stressor). Caregivers and youth will complete three 1-week periods of daily diary assessments spaced 1 month apart to assess short-term STB risk. Remote follow-up assessments will occur every 6 months to examine long-term STB risk. This project will have a high impact on the field by examining early pathways to STB risk and identifying intervention points to offset negative trajectories.

项目摘要/摘要 尽管误解了幼儿没有经历自我伤害的思想和行为（STB），但 来自包括9岁以下儿童的青年样本的数据表明，自杀想法的比率 11％–19％，非自杀自伤为6.2％–21％，自杀未遂在2.4％–3.5％之间。尽管很少见 幼儿自杀死亡率正在增加。但是，幼儿的STB的发展 非常了解。我们团队的研究表明，威胁暴露历史与 年轻人中STB的风险。此外，威胁经历的数据支持增加了STB的风险 通过增强的情绪反应性和反应性攻击。大部分工作都在研究 在许多孩子有很多孩子之后，STB的发展的威胁暴露于STB的发展。 经验丰富的威胁和STB为一些年轻人而发展之后。当前研究的目的是 测试我们概念模型的关键组成部分认为，暴露于威胁的历史会引发发展 - 通过影响情绪反应的影响，幼儿对早期STB的较早风险的心理途径 和反应性侵略性。此外，在未来威胁和 发生非威胁的负面事件，强调需要了解潜在的短期风险（即 幼儿中的STB的日子。该提案的目标1将调查更严重的程度 多重威胁暴露导致5-9岁的幼儿STB的早期出现。 AIM 2意志 将情绪反应性和反应性侵略作为STB的预测因素，包括短期（天）和 长期（月）预测因素，以及威胁可能影响STB的机制。目标3意志 检查未来威胁和非威胁性负面事件的程度，扩大了短期和长期风险 具有情感反应性和反应性侵略性的幼儿中的STB。我们将进行探索性 分析测试我们的完整模型，以提高情绪反应性影响STB 和反应性侵略性，尤其是在发生未来威胁或非威胁事件时。我们还将探索性 和幼儿STB的种族差异。我们将注册300名5至7岁的孩子的历史 威胁暴露及其照顾者在大致多样化的集水区中，并纵向关注青年 2年（直到7-9岁）。青年和看护人将完成由由 多种方法，包括临床访谈；问卷；和观察性，生理学（即 呼吸窦芳香族），以及在发育中相关的负面情绪中采取的行为措施 上下文（例如，社会评估压力源）。看护人和青年将完成三个1周的每日时间 日记评估间隔1个月，以评估短期STB风险。远程后续评估将 每6个月发生一次检查长期STB风险。该项目将对该领域产生重大影响 检查早期通往STB风险的途径并确定干预点以抵消负轨迹。