ONE STEP ANTIMICROBIAL SURGICAL PREPARATION AND DRAPE

描述(改编自申请人的摘要)：手术伤口 感染是发病、死亡和过度的重要原因 医院费用。手术伤口感染排在第二位。 发现全部医院感染，在外科患者中，外科患者 伤口是最常见的医院感染部位。这样做的目的是 该项目是开发独特的涂料配方，可用于 取代目前的三步擦洗/消毒/悬垂术前程序 一步法、缓释、抗菌、术前皮肤 也可用作外科切割窗帘的制剂。涂层是 以液体的形式应用。在不到一分钟的时间里，一个坚韧、单薄、干燥、非 俗气的，不油腻的，“透气”的电影被创造出来。该涂料符合 皮肤的轮廓和放置的位置相适应，不起皱，撕裂， 举起，或冒泡。申请后，8年内完好无损。 小时或更长时间，但可以随时轻松移除，或将自发 雪花持续了大约24小时。 建议的商业应用： 消除目前使用单独抗菌剂的做法 准备和粘性切割窗帘将降低成本 材料，减少准备时间，减少麻醉所需的时间。 此外，一种抗菌制剂和切割窗帘的组合 可统一应用于矫形外科、心脏外科和 神经外科手术将通过减少患者的发病率而受益 感染，从而提高手术成功的机会和 限制因医院外科手术而延长术后住院时间 感染。

DESCRIPTION (Adapted from applicant's abstract): Surgical wound infections are an important cause of morbidity, mortality, and excess hospital costs. Surgical wound infections are the second most frequently found nosocomial infection overall and, among surgical patients, surgical wounds are the most common nosocomial infection site. The goal of this project is to develop unique coating formulations which can be used to replace the current 3-step scrub/disinfect/drape preoperative procedure with a one-step, sustained release, antimicrobial, preoperative skin preparation that also serves as a surgical incise drape. The coating is applied in liquid form. In less than a minute, a tough, thin, dry, non- tacky, non-greasy, "breathable" film is created. The coating conforms to the contour of the skin and fits where placed without wrinkling, tearing, lifting, or bubbling. After application, it will remain intact for 8 hours or more but can easily be removed at anytime or will spontaneously flake away over about 24 hours. PROPOSED COMMERCIAL APPLICATION: Eliminating the current practice of using separate antimicrobial preparations and adhesive incise drapes would cut down on the cost of materials, reduce prep time, and decrease the time needed for anesthesia. Furthermore, a combination antimicrobial preparation and incise drape that could be uniformly applied in orthopaedic surgery, cardiac surgery, and neurosurgery would benefit the patient by reducing the incidence of infection, thereby improving the chances of successful surgery and limiting prolonged post-operative hospital stay due to nosocomial surgical infection.