ONE STEP ANTIMICROBIAL SURGICAL PREPARATION AND DRAPE

描述（改编自申请人摘要）：手术伤口 感染是发病率、死亡率和过剩的一个重要原因， 医院费用。手术伤口感染是第二常见的 发现整体医院感染，在外科患者中， 伤口是最常见的医院感染部位。 这个目标 项目是开发独特的涂料配方，可用于 替换当前的3步擦洗/消毒/铺巾术前程序 一步式缓释抗菌术前皮肤 也可用作外科手术切口铺巾的制剂。 涂层 以液体形式使用。 在不到一分钟的时间里，一个坚韧，薄，干燥，非- 产生粘性、非油腻、“透气”的膜。 涂层符合 皮肤的轮廓和适合的地方放置没有扭曲，撕裂， 提升或冒泡。 使用后，它将保持完整8 小时或更长时间，但可以随时轻松移除或自发移除 会在24小时内剥落 拟定商业应用： 消除目前使用单独抗菌剂的做法 准备和粘合剂切割窗帘将减少成本， 材料，减少准备时间，减少麻醉所需的时间。 此外，还提供了一种抗微生物制剂和切割铺巾的组合， 可统一应用于骨科手术、心脏手术， 神经外科手术将通过减少 感染，从而提高手术成功的机会， 限制了由于医院外科手术导致的术后住院时间延长 感染

DESCRIPTION (Adapted from applicant's abstract): Surgical wound infections are an important cause of morbidity, mortality, and excess hospital costs. Surgical wound infections are the second most frequently found nosocomial infection overall and, among surgical patients, surgical wounds are the most common nosocomial infection site. The goal of this project is to develop unique coating formulations which can be used to replace the current 3-step scrub/disinfect/drape preoperative procedure with a one-step, sustained release, antimicrobial, preoperative skin preparation that also serves as a surgical incise drape. The coating is applied in liquid form. In less than a minute, a tough, thin, dry, non- tacky, non-greasy, "breathable" film is created. The coating conforms to the contour of the skin and fits where placed without wrinkling, tearing, lifting, or bubbling. After application, it will remain intact for 8 hours or more but can easily be removed at anytime or will spontaneously flake away over about 24 hours. PROPOSED COMMERCIAL APPLICATION: Eliminating the current practice of using separate antimicrobial preparations and adhesive incise drapes would cut down on the cost of materials, reduce prep time, and decrease the time needed for anesthesia. Furthermore, a combination antimicrobial preparation and incise drape that could be uniformly applied in orthopaedic surgery, cardiac surgery, and neurosurgery would benefit the patient by reducing the incidence of infection, thereby improving the chances of successful surgery and limiting prolonged post-operative hospital stay due to nosocomial surgical infection.