SCATTER FACTOR AND AIDS-RELATED KAPOSIS SARCOMA

分散因子和艾滋病相关的卡波西斯肉瘤

• 批准号: 2700568
• 负责人: PETER John POLVERINI
• 金额: $ 31.54万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-07-01 至 2000-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2700568
• 关键词: AIDS; AIDS related neoplasm /cancer; Kaposi's sarcoma; angiogenesis; athymic mouse; cell adhesion molecules; cytokine; enzyme linked immunosorbent assay; genetically modified animals; growth factor; human tissue; laboratory rat; mesenchyme; neoplastic cell; neoplastic transformation; pathologic process; phenotype; simian virus 40; transfection; vascular endothelium; viral carcinogenesis

项目成果

Growth of human blood vessels in severe combined immunodeficient mice. A new in vivo model system of angiogenesis.

严重联合免疫缺陷小鼠体内人类血管的生长。

• DOI: 10.1385/1-59259-332-1:161
• 发表时间: 2003
• 期刊: Methods in molecular medicine.
• 作者: Polverini,PeterJ;Nor,JacquesE;Peters,MartinC;Mooney,DavidJ
• 通讯作者: Mooney,DavidJ

Apoptosis and predisposition to oral cancer.

• DOI: 10.1177/10454411990100020201
• 发表时间: 1999
• 期刊: Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists
• 作者: P. Polverini;J. Nör

Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice.

• 发表时间: 1997-03
• 期刊: Laboratory investigation; a journal of technical methods and pathology
• 作者: K. Lamszus;Liang Jin;A. Fuchs;E. Shi;S. Chowdhury;Yan Yao;P. Polverini;J. Laterra;I. Goldberg-I.

Expression of costimulatory molecules CD80 and/or CD86 by a Kaposi's sarcoma tumor cell line induces differential T-cell activation and proliferation.

• DOI: 10.1006/clim.1999.4712
• 发表时间: 1999-06
• 期刊: Clinical immunology
• 影响因子: 8.6
• 作者: K. Foreman;T. Wrone-Smith;A. Krueger;B. Nickoloff

Scatter factor binds to thrombospondin and other extracellular matrix components.

散射因子与血小板反应蛋白和其他细胞外基质成分结合。

• 发表时间: 1996
• 期刊: The American journal of pathology.
• 作者: Lamszus,K;Joseph,A;Jin,L;Yao,Y;Chowdhury,S;Fuchs,A;Polverini,PJ;Goldberg,ID;Rosen,EM
• 通讯作者: Rosen,EM