DC HIV RELATED MALIGNANCY TISSUE/BIOLOGICAL FLUIDS BANK

这项建议的目标是制定一个全面的、方便用户的、 一个个体的组织和生物液体标本库 显示出艾滋病相关的恶性肿瘤 该银行的材料将 对发病机理感兴趣的研究人员以及 寻求改善艾滋病毒相关疾病的诊断测试和治疗， 恶性肿瘤。 美国艾滋病中心的一个标本库 流行病允许妇女，儿童和有色人种的材料被 很好的代表。 这样的组织库将满足广泛的需求。 艾滋病毒相关恶性肿瘤领域的各种研究人员。 到 为了实现这一目标，我们将建立哥伦比亚特区艾滋病毒相关的预防中心， 来自医院集团的组织/生物液体库联盟 为所有艾滋病毒感染者提供大部分护理， 在华盛顿特区大都会区的个人。 华盛顿特区HIV相关组织/生物液体库联盟 将收集，保存和维护一个全面的质量银行， 患者的所有肿瘤过程的组织和液体标本， 艾滋病。 将建立一个质量保证系统， 收集和保存过程，并确保质量 分发给个别调查人员的材料。 行政 将建立一个结构，以保持病人的保密性， 向调查人员提供关于来源的准确信息， 标本 将保留每名患者的准确摘要医疗记录 参与华盛顿特区HIV相关组织/生物液体库， 允许临床与生物学发现相关。

The goal of this proposal is to develop a comprehensive, user-friendly, bank of tissue and biological fluid specimens from individuals demonstrating HIV-related malignancies. Material from this bank will be available for researchers interested in pathogenesis, as well as those seeking to improve the diagnostic tests and therapies for HIV-related malignancies. A specimen bank in an epicenter of the U.S. HIV/AIDS epidemic allows material from women, children and people of color to be well represented. Such a tissue bank will meet the needs of a wide variety of investigators in the field of HIV-related malignancies. To achieve this goal we will establish the D.C. HIV-Related Malignancy Tissue/Biological Fluid Bank Consortium from the group of hospitals providing the majority of care to individuals of all HIV-infected individuals in the metropolitan D.C. area. The D.C. HIV-Related Malignancy Tissue/Biological Fluid Bank Consortium will collect, preserve, and maintain a comprehensive bank of quality tissue and fluid specimens of all neoplastic processes from patients with HIV disease. A quality assurance system will be established to monitor the collection and preservation processes and ensure the quality of material distributed to individual investigators. An administrative structure will be implemented to maintain patients confidentiality while providing investigators accurate information regarding the source of the specimens. Accurate abstracted medical records will be maintained on each patient participating in the D.C. HIV-Related Tissue/Biological Fluid Bank to allow clinical correlation to biologic findings.