课题基金 / 基金详情

MOLECULAR CLONING OF CARNITINE/ACYLCARNITINE TRANSLOCASE

MOLECULAR CLONING OF CARNITINE/ACYLCARNITINE TRANSLOCASE
肉碱/酰基肉碱转位酶的分子克隆
批准号：
2555865
负责人：
TOD GULICK
金额：
$8.55万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-03-01 至 2000-02-29
来源：
https://reporter.nih.gov/project-details/2555865
关键词：
carnitine complementary DNA fibroblasts gene mutation human genetic material tag mitochondria mitochondrial DNA molecular cloning nucleic acid sequence protein structure function structural genes tissue /cell culture transport proteins

项目摘要

项目成果

TOD GULICK的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
DESCRIPTION (Adapted from applicant's description): The objective of this project is the cloning of the gene encoding mitochondrial carnitine/acylcarnitine translocase. The new set of Specific Aims include: 1) cloning and sequencing of the human CAC, cDNA and structural gene, 2) sequencing of CAC deficiency mutant genes, 3) examination of the expression of the mutant genes in mutant fibroblast cell lines, 4) creation of mutants in a yeast gene, yOR100c, that they believe to be yeast CAC and assessment of its genetic function, and 5) assaying CAC activity in mammalian cells in which mutant and wild-type CAC has been introduced.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
An interdisciplinary approach to elucidate mechanisms of muscle lipotoxicity
Mitochondrial Nucleotide Carriers of NRTI Metabolites
  • 批准号：
    6804111
  • 项目类别：
  • 资助金额：
    $38.56万
  • 财政年份：
    2003
  • 负责人：
    TOD GULICK
  • 依托单位：
    MASSACHUSETTS GENERAL HOSPITAL
Mitochondrial Nucleotide Carriers of NRTI Metabolites
  • 批准号：
    6936621
  • 项目类别：
  • 资助金额：
    $38.56万
  • 财政年份：
    2003
  • 负责人：
    TOD GULICK
  • 依托单位：
    MASSACHUSETTS GENERAL HOSPITAL
Mitochondrial Nucleotide Carriers of NRTI Metabolites
  • 批准号：
    7115805
  • 项目类别：
  • 资助金额：
    $37.48万
  • 财政年份：
    2003
  • 负责人：
    TOD GULICK
  • 依托单位：
    MASSACHUSETTS GENERAL HOSPITAL
海外基金