EPIDEMIOLOGY OF CARDIAC DEVELOPMENT IN YOUTH

青少年心脏发育的流行病学

• 批准号: 2771617
• 负责人: DARWIN R. LABARTHE
• 金额: $ 3.74万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 1999-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2771617
• 关键词: adolescence (12-20); anatomy; body composition; child (0-11); child physical development; epidemiology; gender difference; heart; heart function; human data; human puberty; longitudinal human study; racial /ethnic difference

DESCRIPTION (Adapted from the applicant's abstract) The goal of this research is to elucidate on the basis of a mixed longitudinal design the changes in cardiac structure and function which occur during late childhood and adolescence. Four aims are presented: 1) to document the nature and extent of changes in cardiac structure, based on M-mode measurements and indices and develop corresponding reference values; 2) to document the nature and extent of GENDER AND MINORITIES Of the 678 participants enrolled in Project HeartBeat!, 136 (20.1%) were African-American, 506 (74.6%) were Caucasian, 25 (3.7%) were Hispanic, 7 (1%) were Asian, and 4 (0.6%) were Native American. 333 (49.1%) were female and 345 (50.9%) were male. Completeness of follow-up by gender and ethnicity is not provided. 81.4% of the total study group attended all scheduled examinations, and 90.9% of subjects eligible for at least 10 examinations completed 10 or more exams. BUDGET Under Other Expenses in Year 1, the budget for "Publications, presentations, (graphics, page charges)" is reduced from $1000 to $250, since most of the costs incurred in this category will occur in Year 2. Two full years at the FTE proposed appears excessive for the work described, given the expertise of the team. It is recommended to reduce the funding period to 18 months, and therefore reduce the requested budget for Year 2 by one-half.

描述 （改编自申请人的摘要）这项研究的目标是 在混合纵向设计的基础上阐明心脏的变化 结构和功能发生在儿童晚期和青春期。 提出了四个目标：1）记录变化的性质和程度 心脏结构，基于 M 模式测量和指数并开发 相应的参考值； 2）记录的性质和范围 性别和少数群体 在参加 Project HeartBeat! 的 678 名参与者中，有 136 名 (20.1%) 非裔美国人，506 名 (74.6%) 为白人，25 名 (3.7%) 为西班牙裔，7 名 (1%) 是亚洲人，4 人 (0.6%) 是美洲原住民。 333 名 (49.1%) 为女性 345 名（50.9%）为男性。 按性别和性别划分的后续行动的完整性 未提供种族。 整个研究组的 81.4% 参加了所有 预定的考试，90.9%的科目有资格参加至少 10 考试 完成 10 门或以上考试。 预算 在第一年的其他费用下，“出版物、演示文稿、 （图形、页面费用）”从 1000 美元减少到 250 美元，因为大多数 该类别产生的费用将发生在第二年。两年一整年 考虑到专业知识，拟议的 FTE 对于所描述的工作来说似乎过多 团队的。 建议将资助期限缩短至18个月， 因此，将第二年的预算要求减少一半。