From gene to duty: the emergence of the complex brain

该项目旨在确定负责非人类灵长类动物视觉皮质扩张的分子密码(基因及其产物)，这是形成离散功能和解剖区域的基础。该项目将详细说明在大脑发育的关键阶段表达的所有基因，以及干扰它们的表达如何抑制区域的正常形成。预期的结果是一张支持复杂灵长类视觉皮质形成的分子密码的时间顺序和功能图。这将有助于确定导致复杂灵长类视觉大脑进化的机制，并补充全球正在进行的众多脑连接组研究。

This project aims to determine the molecular code (genes and their products) responsible for the expansion of the nonhuman primate visual cortex, which underpins the formation of discrete functional and anatomical areas. The project will detail all the genes expressed at key stages of brain development and how interfering with their expression inhibits the normal formation of areas. The expected outcomes are a chronological and functional map of the molecular code that underpins the formation of the complex primate visual cortex. This will contribute to defining the mechanisms leading to the evolution of the complex primate visual brain and complement the numerous brain connectome studies being undertaken globally.