1999 GORDON CONFERENCE--COLLAGEN

1999年戈登会议--胶原蛋白

• 批准号: 2807301
• 负责人: Gerard Karsenty
• 金额: $ 1.8万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2807301
• 关键词: aging; collagen; collagen disorder; connective tissue; connective tissue development; fibrosis; liver disorder; mammary disorder; meeting /conference /symposium; protein structure; rheumatoid arthritis; skeletal disorder; skin disorder; travel

The Collagen Gordon Conference has convened every other year since 1970, consequently the 1999 Conference will mark its 29th anniversary. The Collagen Gordon Conference continues to be the premier conference for investigators studying the structure and pathology of connective tissues. Over the years, it has proven to be a unique forum for interaction of an international group of scientists with a common interest in connective tissue biology and diseases. Major discoveries in extracellular matrix research have often been reported for the first time at this conference in the basic biology, development, and diseases of collagen. Diseases highlighted at the 1999 Collagen Gordon Conference will include liver fibrosis (control of collagen synthesis), diseases of the skin, skeleton, breast, kidney, cardiovasculature, rheumatoid arthritis and aging. All aspects of collagen developmental biology and structure are highly relevant to normal function and diseases of the eye. In the area of dental research, collagens play a vital role in the induction of bone formation and tooth structure. The 1999 conference will also emphasize new information regarding the structure, function and assembly of extracellular matrix proteins, the regulation of the genes encoding these proteins during differentiation and development, the phenotypic and metabolic consequences of collagen mutations or gene deletion in humans and transgenic mice, and the role of individual collagen epitopes in diseases. Internationally recognized connective tissue biologists as well as up-and-coming investigators will be invited to present their most exciting work. The Conference has provided an invaluable opportunity for development of productive collaboration among established scientists and between established and new scientists; those collaborations have in turn further enhanced the scientific progress of the field. To ensure the success of this conference by participation of the highest caliber scientists and presentation of the most innovative research, we request funds for partial support of the 1999 Collagen Gordon Conference. The funds will be used to partially defray conferee travel expenses and registration fees.

自1970年以来，胶原蛋白戈登会议每隔一年召开一次，因此1999年会议将纪念其29周年。 胶原蛋白戈登会议仍然是研究结缔组织结构和病理学的研究人员的首要会议。 多年来，它已被证明是一个独特的论坛，为国际科学家团体的互动与结缔组织生物学和疾病的共同利益。 细胞外基质研究的重大发现往往在胶原蛋白的基础生物学、发育和疾病方面首次在本次会议上报道。1999年胶原蛋白戈登会议上强调的疾病将包括肝纤维化（胶原蛋白合成的控制）、皮肤、骨骼、乳房、肾脏、心血管疾病、类风湿性关节炎和衰老。 胶原蛋白发育生物学和结构的所有方面与眼睛的正常功能和疾病高度相关。 在牙科研究领域，胶原蛋白在诱导骨形成和牙齿结构中起着至关重要的作用。 1999年的会议还将强调有关细胞外基质蛋白的结构、功能和组装的新信息，在分化和发育过程中编码这些蛋白的基因的调节，人类和转基因小鼠中胶原蛋白突变或基因缺失的表型和代谢后果，以及单个胶原蛋白表位在疾病中的作用。国际公认的结缔组织生物学家以及未来的研究人员将被邀请介绍他们最令人兴奋的工作。 这次会议为在老科学家之间以及老科学家和新科学家之间发展富有成效的合作提供了宝贵的机会;这些合作反过来又进一步促进了该领域的科学进步。 为了确保本次会议的成功，让最优秀的科学家参与并展示最具创新性的研究，我们请求资金为1999年胶原蛋白戈登会议提供部分支持。 这笔资金将用于支付部分会议差旅费和注册费。