Integrating quantum hyperpolarisation in nuclear magnetic resonance systems

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This project aims to integrate quantum hyperpolarisation technology into state-of-the-art nuclear magnetic resonance (NMR) systems, potentially boosting the signal by several orders of magnitude. Understanding the structure and function of membrane bound peptides and proteins in cells in their native environments is critical in drug development. However, studying these biomolecules by conventional NMR under ambient conditions is challenging due to sensitivity limitations. The technology developed by this project will be a significant step forward in NMR and the new science enabled may have far reaching consequences for the study of peptides and proteins of live cells for the development of new drugs and anti-biotics, with direct societal benefits and flow-on economic benefits.