Novel wearable neurostimulation system to target period pain

针对痛经的新型可穿戴神经刺激系统

• 批准号: 97066
• 金额: $ 28.55万
• 依托单位: ELECTRONRX LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=97066
• 关键词: Novel; wearable; neurostimulation; system; target

**Problem**It is calculated that 80% of women of reproductive age (1.5bn people worldwide) suffer from period pain at some point in their life. The pain is felt as either intense spasms or dull and constant cramps in the abdomen which can spread to the back and thighs. Most women suffer the pain in silence, however it disrupts their daily and working lives and in extreme cases requires a hysterectomy. Currently, there are no effective, long term, side-effect free treatments to deal with period pain. Most women use over the counter painkillers, often ibuprofen. However, this gives short lasting relief, is ineffective for people with severe pain and can have several side effects if used long term. Other treatments are hormonal contraceptives, surgery or self-help measures, however these have either major side effects, including an increased risk of blood clots and heart attacks, or give limited pain relief.**The Ohmm Solution**This project was born with the intention of giving women around the world control back during their periods. We are developing a novel neurostimulation device, based on extensive scientific evidence that targets the cause of period pain, providing long lasting drug-free pain relief.The device will be worn on top of the painful area, either the abdomen or lower back, and provide pain relief by an anti-inflammatory mechanism. It has been designed in collaboration with period pain sufferers to be small, comfortable, lightweight, discreet and can even be worn while exercising or doing other activities. It is wirelessly controlled by a paired smartphone app, and activated only when it is needed. Ohmm’s treatment can be personalised, allowing the user to select the most effective, comfortable, pain relieving settings. Ohmm gives women the chance to treat their pain whenever they need it in a discreet, customizable way, leaving them free to carry out their daily routines and contribute to society and the economy without fear of period pain.

**问题**据计算，80%的育龄女性(全球15亿人)在她们生命中的某个时刻遭受月经疼痛的折磨。疼痛的感觉要么是剧烈的痉挛，要么是腹部迟钝而持续的抽筋，这可能会蔓延到背部和大腿。大多数女性默默地承受着痛苦，但这会扰乱她们的日常和工作生活，在极端情况下需要子宫切除术。目前，还没有有效的、长期的、无副作用的治疗方法来治疗经期疼痛。大多数女性使用非处方止痛药，通常是布洛芬。然而，这会带来短暂的持久缓解，对剧烈疼痛的人无效，如果长期使用可能会产生几种副作用。其他的治疗方法是荷尔蒙避孕药、手术或自助措施，然而，这些要么有很大的副作用，包括增加血栓和心脏病发作的风险，要么只能起到有限的缓解疼痛的作用。**欧姆解决方案**这个项目诞生的目的是让世界各地的女性重新控制她们的经期。我们正在开发一种新型的神经刺激装置，基于广泛的科学证据，针对经期疼痛的原因，提供长期的无药物止痛。该装置将佩戴在疼痛区域的顶部，无论是腹部还是下背部，并通过抗炎机制提供疼痛缓解。它是与痛经患者合作设计的，小巧、舒适、轻便、谨慎，甚至可以在锻炼或进行其他活动时佩戴。它由一款配对的智能手机应用程序无线控制，只有在需要时才会激活。OHMM的治疗可以是个性化的，允许用户选择最有效、最舒适、最缓解疼痛的设置。OHMM让女性有机会在需要的时候以一种谨慎的、可定制的方式治疗疼痛，让她们自由地进行日常工作，为社会和经济做出贡献，而不必担心经期疼痛。